ID   TOLB_ANAMM              Reviewed;         441 AA.
AC   Q5PBH8;
DT   07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=AM244;
OS   Anaplasma marginale (strain St. Maries).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Anaplasmataceae; Anaplasma.
OX   NCBI_TaxID=234826;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=St. Maries;
RX   PubMed=15618402; DOI=10.1073/pnas.0406656102;
RA   Brayton K.A., Kappmeyer L.S., Herndon D.R., Dark M.J., Tibbals D.L.,
RA   Palmer G.H., McGuire T.C., Knowles D.P. Jr.;
RT   "Complete genome sequencing of Anaplasma marginale reveals that the surface
RT   is skewed to two superfamilies of outer membrane proteins.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:844-849(2005).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; CP000030; AAV86351.1; -; Genomic_DNA.
DR   RefSeq; WP_010263042.1; NZ_AFMU01000015.1.
DR   AlphaFoldDB; Q5PBH8; -.
DR   SMR; Q5PBH8; -.
DR   KEGG; ama:AM244; -.
DR   HOGENOM; CLU_047123_0_0_5; -.
DR   OMA; DIYGPGQ; -.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 3.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Signal.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           26..441
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_0000034621"
SQ   SEQUENCE   441 AA;  47742 MW;  5964251A5642AC2B CRC64;
     MRIFFFAYVL PTVISLLLGC QGAIAALGVD ITKGNTEKVK ISVAPMHSST NLEKEIGKSC
     IRVMLRDLNS TGIFDASWKL PAGGFSTTSE GMPDSNAWTS VAKDVLVTGS IKEFAQGRVK
     VKLFIWDVAS GRQLSGKSFN FATGNWRRAA HSMSDSIYSR ITGEGGYFNT RIAYVAETGL
     PGSRRIAIMD QDGANNIYIT GRGEFVSTPR FSPDARNLVY MSYAKSGGSV VLHDLETGYS
     TALGGVRGVN SSPRFSPDGR HVLLSESAQG STNIYSIDLK SGKSTRLTND RSINTSASYS
     PDKKSIVFNS DRSGRPQLYV MNADGTNQRR ISSGKGGYSA PAWSPRGDWI AFTKTEGKSF
     HVGVMKPDGS GERLLAKGYM VDSPSWSPNG RVILFTQQDP PSATHPFRSR LVTVDITGTN
     TQILDVPTNA SNAHWSPVLR E