ID   TOLB_BRUC2              Reviewed;         443 AA.
AC   A9M7J5;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=BCAN_A1736;
OS   Brucella canis (strain ATCC 23365 / NCTC 10854).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=483179;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23365 / NCTC 10854;
RA   Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J., Dharmanolla C.,
RA   Gillespie J.J., Kenyon R.W., Lu J., Mane S., Mohapatra S., Nagrani S.,
RA   Purkayastha A., Rajasimha H.K., Shallom J.M., Shallom S., Shukla M.,
RA   Snyder E.E., Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H.,
RA   Bruce D., Detter C., Munk C., Brettin T.S.;
RT   "Brucella canis ATCC 23365 whole genome shotgun sequencing project.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; CP000872; ABX62742.1; -; Genomic_DNA.
DR   RefSeq; WP_004692773.1; NC_010103.1.
DR   AlphaFoldDB; A9M7J5; -.
DR   SMR; A9M7J5; -.
DR   EnsemblBacteria; ABX62742; ABX62742; BCAN_A1736.
DR   GeneID; 55591317; -.
DR   KEGG; bcs:BCAN_A1736; -.
DR   HOGENOM; CLU_047123_0_0_5; -.
DR   OMA; VREPSWG; -.
DR   PhylomeDB; A9M7J5; -.
DR   Proteomes; UP000001385; Chromosome I.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 3.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Signal.
FT   SIGNAL          1..33
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           34..443
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_1000082940"
SQ   SEQUENCE   443 AA;  48537 MW;  DA1E97090574C061 CRC64;
     MKIGIINTKI RTVFSAFACM IAASLVCTMP ARAVVEININ KGVIEPLPIA ITDFLSADQL
     GSNITSVIAA DLERSGLFAP IDKGAFIEKI SNPDAAPRFE DWKVINAQAL VTGRITKQPD
     GRLKAEFHLW DTFGGQRMIG QQFFTTPDNW RRVAHIIADA IYERLTGDKG YFDTRVVFVD
     ESGPAQKRVK RLAIMDQDGA NVRFISDGRA LSLTPRFSPN RQEVTYMSFE GGSPKVYLLQ
     LETGQRELVG NFPGMTIAPR FSPDGQKVVM SLLQDDGSAN IYTMDLRNRT TTRLTSSQAI
     DTGASYSPDG SQIVFTSDRG GRPQLYVMGA DGSNPRRISM GDGSYSTPVW SPRGDLIAFT
     KQSQGQFSIG VMKTDGSGER LLTSGFHNEG PTWAPNGRVL MFFRKAAGAG GPKLFTIDLT
     GRNERQIQTP NFASDPAWSP LLE