ID   TOLB_BURCH              Reviewed;         431 AA.
AC   A0K4X6;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671};
GN   OrderedLocusNames=Bcen2424_0800;
OS   Burkholderia cenocepacia (strain HI2424).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=331272;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HI2424;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P.,
RA   Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Kim E., LiPuma J.J., Gonzalez C.F.,
RA   Konstantinidis K., Tiedje J.M., Richardson P.;
RT   "Complete sequence of chromosome 1 of Burkholderia cenocepacia HI2424.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; CP000458; ABK07553.1; -; Genomic_DNA.
DR   RefSeq; WP_006476798.1; NC_008542.1.
DR   AlphaFoldDB; A0K4X6; -.
DR   SMR; A0K4X6; -.
DR   KEGG; bch:Bcen2424_0800; -.
DR   HOGENOM; CLU_047123_0_0_4; -.
DR   OMA; VREPSWG; -.
DR   OrthoDB; 821953at2; -.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 4.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Signal.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           27..431
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_5000164641"
FT   REGION          406..431
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   431 AA;  45755 MW;  A3F7067DD2AF59C5 CRC64;
     MSLMTKLGFR ALVASCLITA GSAANAQVNV LITGVGSTQF PIATANFTNE ANLPQQVTSI
     VRADLARSGK FTNIDAGSTP VPETASVDLG AWKAKGANAF VAGSVNRDAN GQYKVNFILY
     DTVKQQSLGG LSLTATDTTL RTAGHKIADY IYQKLLGVRG VFATRLSYVI KTGNRYQLQI
     SDSDGQNARI ALSSTEPIIS PAWSPSGTKV AYVSFERKKP IVYIHDLPTG RRYMVSDQKG
     NNSAPAWSPD SNTLAVALSL TGNTQIYTVN ANGGGLRRLT QSSSIDTEPF YSPDGRWIYF
     TSDRGGAPQI YRMPAQGESA GAAQRVTFTG SYNTSPRVSP DGKLLAYISR TGGGFKLYVQ
     DLQTGAANAI TNTNRDESPS FAANGQYVLY ATQSGGRNVL AAVPSDGSAP PQILSVQGGS
     VREPSWGPFM Q