ID   TOLB_BURM1              Reviewed;         431 AA.
AC   A9AFQ0;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671};
GN   OrderedLocusNames=Bmul_2587, BMULJ_00651;
OS   Burkholderia multivorans (strain ATCC 17616 / 249).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=395019;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17616 / 249;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J.,
RA   Richardson P.;
RT   "Complete sequence of chromosome 1 of Burkholderia multivorans ATCC
RT   17616.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17616 / 249;
RA   Ohtsubo Y., Yamashita A., Kurokawa K., Takami H., Yuhara S., Nishiyama E.,
RA   Endo R., Miyazaki R., Ono A., Yano K., Ito M., Sota M., Yuji N.,
RA   Hattori M., Tsuda M.;
RT   "Complete genome sequence of Burkholderia multivorans ATCC 17616.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; CP000868; ABX16271.1; -; Genomic_DNA.
DR   EMBL; AP009385; BAG42614.1; -; Genomic_DNA.
DR   RefSeq; WP_012214041.1; NC_010804.1.
DR   AlphaFoldDB; A9AFQ0; -.
DR   SMR; A9AFQ0; -.
DR   STRING; 395019.Bmul_2587; -.
DR   EnsemblBacteria; BAG42614; BAG42614; BMULJ_00651.
DR   KEGG; bmj:BMULJ_00651; -.
DR   KEGG; bmu:Bmul_2587; -.
DR   eggNOG; COG0823; Bacteria.
DR   HOGENOM; CLU_047123_0_0_4; -.
DR   OMA; VREPSWG; -.
DR   Proteomes; UP000008815; Chromosome 1.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 5.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           27..431
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_5000285140"
FT   REGION          411..431
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   431 AA;  45618 MW;  0BC57F521E15E38F CRC64;
     MSLMTKLGFR ALVASCLIAA GSAANAQVNV LITGVGSTQF PIATANFANE AGLPQQVTSI
     VRADLARSGK FTNIDAGSTP VPETASVDLG AWKAKGANAF VAGSVNHEGN GQYKINFILY
     DTVKQQSLGG LSLSANDTTL RTAGHKIADY IYQKLLGVRG VFATRLSYVI KTGNRYQLQI
     SDSDGQNARI ALSSTEPIIS PAWSPSGTKV AYVSFERKKP IVYIHDLPTG RRYMVSDQKG
     NNSAPAWSPD GNTLAVALSL TGNTQIYSVN SNGGGLRRLT QSSSIDTEPF YSPDGRWIYF
     TSDRGGAPQI YRMPAQGESA GAAQRVTFTG SYNTSPRVSP DGKLLAYISR TGGGFKLYVQ
     DLQTGAANAI TNTNRDESPS FAANGQYILY ATQSGGRNVL AAVPSDGSAP PQILSVQGGS
     VREPSWGPFM Q