ID   TOLB_BURPS              Reviewed;         433 AA.
AC   Q63RA8;
DT   07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=BPSL2764;
OS   Burkholderia pseudomallei (strain K96243).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=272560;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K96243;
RX   PubMed=15377794; DOI=10.1073/pnas.0403302101;
RA   Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.-M.,
RA   Atkins T., Crossman L.C., Pitt T., Churcher C., Mungall K.L., Bentley S.D.,
RA   Sebaihia M., Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A.,
RA   Brown N.F., Challis G.L., Cherevach I., Chillingworth T., Cronin A.,
RA   Crossett B., Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z.,
RA   Hauser H., Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S.,
RA   Price C., Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M.,
RA   Simmonds M., Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M.,
RA   Whitehead S., Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J.;
RT   "Genomic plasticity of the causative agent of melioidosis, Burkholderia
RT   pseudomallei.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; BX571965; CAH36772.1; -; Genomic_DNA.
DR   RefSeq; WP_004533572.1; NZ_CP009538.1.
DR   RefSeq; YP_109360.1; NC_006350.1.
DR   AlphaFoldDB; Q63RA8; -.
DR   SMR; Q63RA8; -.
DR   STRING; 272560.BPSL2764; -.
DR   EnsemblBacteria; CAH36772; CAH36772; BPSL2764.
DR   GeneID; 56528433; -.
DR   KEGG; bps:BPSL2764; -.
DR   PATRIC; fig|272560.51.peg.2551; -.
DR   eggNOG; COG0823; Bacteria.
DR   OMA; VREPSWG; -.
DR   Proteomes; UP000000605; Chromosome 1.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 5.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           27..433
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_0000034633"
SQ   SEQUENCE   433 AA;  45894 MW;  6F4943F6E061F064 CRC64;
     MSLMTKLGFR ALVASCLIAA GGAAHAQVNV LITGVGSTQF PIATANFVNE ASLPQQVTSV
     VRGDLARSGK FSNVDAGSTP VPETASVDFG AWKAKGANAF VAGSVNREPN GQYKVNFILY
     DTVKQQSLGG LSLTTSNDNE GMRKTGHKIA DYIYQKLLGV RGVFNTRLSY VQRTGNVYKL
     LISDSDGQNA IPALTSKEPI ISPAWSPSGT KVAYVSFELR KPVVYIHDLP TGRRYVISNQ
     KGNNSAPAWS PDGQTLAVAL SLTGNTQIYS VSSTGTGLRR LTRSSSIDTE PFYSPDGKWI
     YFTSDRGGAP QIYRMPAEGE SAGAAQRVTF TGSYNTSPRV SPDGKLLAYI SRTGGGFKLY
     VQDLQSGAAN AVTNTTRDES PSFAANGQYI LYATQSGGRS VLAAVPSDGS APPQILSVQG
     GAIREPSWGP FMQ