TOLB_CUPMC
ID TOLB_CUPMC Reviewed; 446 AA.
AC Q1LJX8;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2006, sequence version 1.
DT 25-MAY-2022, entry version 88.
DE RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE Flags: Precursor;
GN Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=Rmet_2675;
OS Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 /
OS CH34) (Ralstonia metallidurans).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=266264;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43123 / DSM 2839 / NBRC 102507 / CH34;
RX PubMed=20463976; DOI=10.1371/journal.pone.0010433;
RA Janssen P.J., Van Houdt R., Moors H., Monsieurs P., Morin N., Michaux A.,
RA Benotmane M.A., Leys N., Vallaeys T., Lapidus A., Monchy S., Medigue C.,
RA Taghavi S., McCorkle S., Dunn J., van der Lelie D., Mergeay M.;
RT "The complete genome sequence of Cupriavidus metallidurans strain CH34, a
RT master survivalist in harsh and anthropogenic environments.";
RL PLoS ONE 5:E10433-E10433(2010).
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000352; ABF09548.1; -; Genomic_DNA.
DR RefSeq; WP_011517249.1; NC_007973.1.
DR AlphaFoldDB; Q1LJX8; -.
DR SMR; Q1LJX8; -.
DR STRING; 266264.Rmet_2675; -.
DR PRIDE; Q1LJX8; -.
DR EnsemblBacteria; ABF09548; ABF09548; Rmet_2675.
DR KEGG; rme:Rmet_2675; -.
DR eggNOG; COG0823; Bacteria.
DR HOGENOM; CLU_047123_0_0_4; -.
DR OMA; VREPSWG; -.
DR OrthoDB; 821953at2; -.
DR Proteomes; UP000002429; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR Gene3D; 2.120.10.30; -; 1.
DR HAMAP; MF_00671; TolB; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR014167; Tol-Pal_TolB.
DR InterPro; IPR007195; TolB_N.
DR Pfam; PF07676; PD40; 5.
DR Pfam; PF04052; TolB_N; 1.
DR TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Periplasm; Reference proteome; Signal.
FT SIGNAL 1..43
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT CHAIN 44..446
FT /note="Tol-Pal system protein TolB"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT /id="PRO_0000259075"
SQ SEQUENCE 446 AA; 48010 MW; 4E5221DEC0D1C58E CRC64;
MRKLWAPNWL SRRQNANPTR DQSRHALMAW LAAALMSAGA AHAQLNVEIT GVGSNQFPVA
TANFQGEAQA PQNLTAIIRS DLTNSGRFRN VDPAGATVAE SAQVDLGSWK AKGADAFVAG
SVTPTSNGQY EVRFRLYDTA KGQSLGGLAF TVTQGQLRVT AHKIADYIYE KLLGERGVFA
TRLSYVSKVG NRYQLLISDS DGQNAQIALT STEPIISPAW SPDGRRVAYV SFEAKKPVVY
VHDLATGKRV VVSNQKGNNS APSWSPDGQH LAVSLSRDGN TQIYQVNADG SGLRRLTRSS
AIDTEPQFSP DGRSIYFTSD RGGAPQIYRM PASGEESGAA QRVTFKGSYN VSPRISPDGK
YLAYISRSGG FRLQLQDLSN GDVTSLTDTT NDESPSFAAN GKYILYATRV GGRSVLAAVS
TDGRTKQVLS LQSGAVREPS WGPFMQ
