ID   TOLB_EDWI9              Reviewed;         430 AA.
AC   C5BEL8;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=NT01EI_2857;
OS   Edwardsiella ictaluri (strain 93-146).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Hafniaceae; Edwardsiella.
OX   NCBI_TaxID=634503;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=93-146;
RA   Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C.,
RA   Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.;
RT   "Complete genome sequence of Edwardsiella ictaluri 93-146.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. TolB occupies a key intermediary
CC       position in the Tol-Pal system because it communicates directly with
CC       both membrane-embedded components, Pal in the outer membrane and TolA
CC       in the inner membrane. {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; CP001600; ACR70018.1; -; Genomic_DNA.
DR   RefSeq; WP_015872114.1; NC_012779.2.
DR   AlphaFoldDB; C5BEL8; -.
DR   SMR; C5BEL8; -.
DR   STRING; 67780.B6E78_06210; -.
DR   EnsemblBacteria; ACR70018; ACR70018; NT01EI_2857.
DR   GeneID; 7959499; -.
DR   KEGG; eic:NT01EI_2857; -.
DR   PATRIC; fig|634503.3.peg.2555; -.
DR   HOGENOM; CLU_047123_0_0_6; -.
DR   OMA; VREPSWG; -.
DR   OrthoDB; 821953at2; -.
DR   Proteomes; UP000001485; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 4.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           22..430
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_1000212508"
SQ   SEQUENCE   430 AA;  46048 MW;  2A5262D556B1D0EF CRC64;
     MKQAFRLMVG LLVLWASVLH AEVRIVITQG VDSARPIGVV PFKWMGPGTA PENIGGIIAA
     DLRNSGKFNP IDASRMPQQP SAAAEVSPAA WTALGIDAVV VGQVQPGADG SYLVSYQLVD
     TSGNPGSVLV QNQYKVTGQW LRYAAHTASD EVFEKLTGIK GAFRTRIAYV VQTNGGQFPY
     ELRVADYDGY NQFVVHRSAE PLMSPAWSPD GSKLAYVTFE SGRSALVIQT LSNGAIRQVA
     SFPRHNGSPA FSPDGSKLAF ALSKTGSLNL YVMDLASGAI RQVTDGRSNN TEPTWFPDSQ
     NLAFTSDQAG RPQIYKMNIN GGVAQRLTWE GSQNQDAEVS PDGKFLVMVS SSAGAQHIAK
     LDLGTNATQV LTDTFLDETP SIAPNGTMVI YSSTQGLGSV LQLVSIDGRF KARLPATDGQ
     VKFPAWSPYL