TOLB_FRATH
ID TOLB_FRATH Reviewed; 435 AA.
AC Q2A580;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 04-APR-2006, sequence version 1.
DT 25-MAY-2022, entry version 76.
DE RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE Flags: Precursor;
GN Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=FTL_0334;
OS Francisella tularensis subsp. holarctica (strain LVS).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Thiotrichales;
OC Francisellaceae; Francisella.
OX NCBI_TaxID=376619;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LVS;
RA Chain P., Larimer F., Land M., Stilwagen S., Larsson P., Bearden S.,
RA Chu M., Oyston P., Forsman M., Andersson S., Lindler L., Titball R.,
RA Garcia E.;
RT "Complete genome sequence of Francisella tularensis LVS (Live Vaccine
RT Strain).";
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
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DR EMBL; AM233362; CAJ78774.1; -; Genomic_DNA.
DR RefSeq; WP_004336796.1; NZ_CP009694.1.
DR AlphaFoldDB; Q2A580; -.
DR SMR; Q2A580; -.
DR KEGG; ftl:FTL_0334; -.
DR OMA; DIYGPGQ; -.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR Gene3D; 2.120.10.30; -; 1.
DR HAMAP; MF_00671; TolB; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR014167; Tol-Pal_TolB.
DR Pfam; PF07676; PD40; 3.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Periplasm; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT CHAIN 21..435
FT /note="Tol-Pal system protein TolB"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT /id="PRO_0000259048"
SQ SEQUENCE 435 AA; 48453 MW; CCC27599AACFFD25 CRC64;
MRKIIAGVFI FVFLISNLYA DLVAEVTTGV IQKPLVTVVS DNVVDQFPQQ VNSVMVADLN
HNAKLQANDT IKYEIKQKQN IPWKSLKSDY VVLTKYTNNS YNNYTVEVQI LKRNDTSYLQ
AITYKNINVS LMRTLAHKIS NYVYQKLTGN QGFFLTKLAY VKVSNLYARY GRLYELIISD
YDGYNKHVVL RQTDNPIATP SWSNDGRYIV YSSYSGGSMG VYTLEIATGK VTRITNYKGI
NSSPSFSPDG KEIALALSKG YSDQTNIYIM NLATKALKRI TINGINTAPK FSPNGQSIVF
TSDREGRPNI YVASVNSKYP QSSILSTKIH QAYEPNYTPD GKNIVFMNQS SRTSGTQIAD
FNLVNGSVTN ITNGKADSSP TVSPYGDMVA YISTNTRGYS SLDMVSLDGD NHFNIETADN
GNILIQSPSW SPKNF