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TOLB_FRATM
ID   TOLB_FRATM              Reviewed;         435 AA.
AC   B2SET5;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=FTM_0432;
OS   Francisella tularensis subsp. mediasiatica (strain FSC147).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Thiotrichales;
OC   Francisellaceae; Francisella.
OX   NCBI_TaxID=441952;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FSC147;
RX   PubMed=19521508; DOI=10.1371/journal.ppat.1000472;
RA   Larsson P., Elfsmark D., Svensson K., Wikstroem P., Forsman M., Brettin T.,
RA   Keim P., Johansson A.;
RT   "Molecular evolutionary consequences of niche restriction in Francisella
RT   tularensis, a facultative intracellular pathogen.";
RL   PLoS Pathog. 5:E1000472-E1000472(2009).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; CP000915; ACD30461.1; -; Genomic_DNA.
DR   AlphaFoldDB; B2SET5; -.
DR   SMR; B2SET5; -.
DR   KEGG; ftm:FTM_0432; -.
DR   HOGENOM; CLU_047123_0_0_6; -.
DR   OMA; DIYGPGQ; -.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   Pfam; PF07676; PD40; 3.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           21..435
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_1000131530"
SQ   SEQUENCE   435 AA;  48437 MW;  2CF962BF092CAB36 CRC64;
     MRKIIAGVFI FVFLISNLYA DLVAEVTTGV IQKPLVTVVS DNVVDQFPQQ VNFVIVADLN
     HNAKLQANDT IKYEIKQKQN IPWKSLKSDY VVLTKYTNNS YNNYTVEVQI LKRNDTSYLQ
     AITYKNINVS LMRALAHKIS NYVYQKLTGN QGFFLTKLAY VKVSNPYARY GRLYELIISD
     YDGYNKHVVL RQTDNPIATP SWSNDGRYIV YSSYSGGSMG VYTLEIATGK VTRITNYKGI
     NSSPSFSPDG KEIALALSKG YSDQTNIYIM NLSTKALKRI TINGINTAPK FSPNGQSIVF
     TSDREGRPNI YVASVNSKYP QSSILSTKIH QAYEPNYTPD GKNIVFMNQS SRTSGTQIAD
     FNLANGSVTN ITNGKADSSP TVSPYGDMVA YISTNTRGYS SLDMVSLDGD NHFNIETADN
     GNILIQSPSW SPKNF
 
 
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