TOLB_FRATW
ID TOLB_FRATW Reviewed; 435 AA.
AC A4IYV5;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2007, sequence version 1.
DT 25-MAY-2022, entry version 74.
DE RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE Flags: Precursor;
GN Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=FTW_1346;
OS Francisella tularensis subsp. tularensis (strain WY96-3418).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Thiotrichales;
OC Francisellaceae; Francisella.
OX NCBI_TaxID=418136;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WY96-3418;
RX PubMed=17895988; DOI=10.1371/journal.pone.0000947;
RA Beckstrom-Sternberg S.M., Auerbach R.K., Godbole S., Pearson J.V.,
RA Beckstrom-Sternberg J.S., Deng Z., Munk C., Kubota K., Zhou Y., Bruce D.,
RA Noronha J., Scheuermann R.H., Wang A., Wei X., Wang J., Hao J.,
RA Wagner D.M., Brettin T.S., Brown N., Gilna P., Keim P.S.;
RT "Complete genomic characterization of a pathogenic A.II strain of
RT Francisella tularensis subspecies tularensis.";
RL PLoS ONE 2:E947-E947(2007).
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
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DR EMBL; CP000608; ABO47106.1; -; Genomic_DNA.
DR RefSeq; WP_003026579.1; NC_009257.1.
DR AlphaFoldDB; A4IYV5; -.
DR SMR; A4IYV5; -.
DR KEGG; ftw:FTW_1346; -.
DR HOGENOM; CLU_047123_0_0_6; -.
DR OMA; DIYGPGQ; -.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR Gene3D; 2.120.10.30; -; 1.
DR HAMAP; MF_00671; TolB; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR014167; Tol-Pal_TolB.
DR Pfam; PF07676; PD40; 3.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Periplasm; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT CHAIN 21..435
FT /note="Tol-Pal system protein TolB"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT /id="PRO_1000026702"
SQ SEQUENCE 435 AA; 48329 MW; 180569C5770DB140 CRC64;
MRKIIAGVFI FVFLISNLYA ALVAEVTTGV IQKPLVTVVS DNVVDQFPQQ VNSVIVADLN
HNAKLQANDT IKYEIKQKQN IPWKSLKSDY VVLTKYTNNS YNNYTVEVQI LKRNDTSYLQ
AITYKNINVS LMRTLAHKIS NYVYQKLTGN QGFFLTKLAY VKVSNPYARY GRLYELIISD
YDGYNKHVVL RQTDNPIATP SWSNDGRYIV YSSYSGGSMG VYTLEIATGK VTRITNYKGI
NSSPSLSPDG KEIALALSKG YSDQTNIYIM NLSTKALKRI TINGINTAPK FSPNGQSIVF
TSDREGRPNI YVASVNSKYP QSSILSTKIH QAYEPNYTPD GKNIVFMNQS SRTSGTQIAD
FNLANGSVTN ITNGKADSSP TVSPYGDMVA YISTNTRGYS SLDMVSLDGD NHFNIETADN
GNILIQSPSW SPKNF