TOLB_GEOSL
ID TOLB_GEOSL Reviewed; 432 AA.
AC Q74H67;
DT 07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 96.
DE RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE Flags: Precursor;
GN Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=GSU0025;
OS Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC Geobacteraceae; Geobacter.
OX NCBI_TaxID=243231;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51573 / DSM 12127 / PCA;
RX PubMed=14671304; DOI=10.1126/science.1088727;
RA Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.C.,
RA Heidelberg J.F., Wu D., Wu M., Ward N.L., Beanan M.J., Dodson R.J.,
RA Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S.,
RA Gwinn M.L., Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J.,
RA Davidsen T.M., Zafar N., White O., Tran B., Romero C., Forberger H.A.,
RA Weidman J.F., Khouri H.M., Feldblyum T.V., Utterback T.R., Van Aken S.E.,
RA Lovley D.R., Fraser C.M.;
RT "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT environments.";
RL Science 302:1967-1969(2003).
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
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DR EMBL; AE017180; AAR33360.1; -; Genomic_DNA.
DR RefSeq; NP_951087.1; NC_002939.5.
DR RefSeq; WP_010940703.1; NC_002939.5.
DR AlphaFoldDB; Q74H67; -.
DR SMR; Q74H67; -.
DR STRING; 243231.GSU0025; -.
DR DNASU; 2688562; -.
DR EnsemblBacteria; AAR33360; AAR33360; GSU0025.
DR KEGG; gsu:GSU0025; -.
DR PATRIC; fig|243231.5.peg.26; -.
DR eggNOG; COG0823; Bacteria.
DR HOGENOM; CLU_047123_2_0_7; -.
DR InParanoid; Q74H67; -.
DR OMA; VREPSWG; -.
DR Proteomes; UP000000577; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR Gene3D; 2.120.10.30; -; 1.
DR HAMAP; MF_00671; TolB; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR014167; Tol-Pal_TolB.
DR InterPro; IPR007195; TolB_N.
DR Pfam; PF07676; PD40; 5.
DR Pfam; PF04052; TolB_N; 1.
DR TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Periplasm; Reference proteome; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT CHAIN 22..432
FT /note="Tol-Pal system protein TolB"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT /id="PRO_0000034653"
SQ SEQUENCE 432 AA; 47671 MW; EBD25412A598E558 CRC64;
MKHVRIFATL LALLVISVTP AVIHSEDVYR EVTASGAHNL TLAVDNPRNL GGADDAALAR
DVAEVLRFDM TLAGPFSVMA PPAGTSPGGI RPGEFDLDSW RNAGVDLLVK SGYTITGDSV
TMEFRLYNAT QGRELAAKRY TGKRSDLRRI THTFSDDIMQ TMTGERGPFT GKIAFVSTES
GNKEIYLMDY DGHNVQRLTK NRSINLNPDF SPNGRELAYT SYRRGNPDLF RREIFTGTEA
VVSSHRGINV TGTWSPDGKQ LALAMSRDGN SEIYAISRDG RDPRRLTTHQ AIDVSPAWSP
DGKRIAFVSD RLGKPQVFIM NADGSDVRRL TTSGAYNVSP RWSPKGDRLV YCRQEGGFQI
YSIATDGTGD TRLTSEGSNE HPRWSPDGRF LTFSSTRDGG EAIYVMRSDG SGQTRVYRSK
GKASHPTWSP RW