ID   TOLB_HAEDU              Reviewed;         426 AA.
AC   Q7VKU3;
DT   07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=HD_1773;
OS   Haemophilus ducreyi (strain 35000HP / ATCC 700724).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=233412;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=35000HP / ATCC 700724;
RA   Munson R.S. Jr., Ray W.C., Mahairas G., Sabo P., Mungur R., Johnson L.,
RA   Nguyen D., Wang J., Forst C., Hood L.;
RT   "The complete genome sequence of Haemophilus ducreyi.";
RL   Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; AE017143; AAP96527.1; -; Genomic_DNA.
DR   RefSeq; WP_010945556.1; NC_002940.2.
DR   AlphaFoldDB; Q7VKU3; -.
DR   SMR; Q7VKU3; -.
DR   STRING; 233412.HD_1773; -.
DR   EnsemblBacteria; AAP96527; AAP96527; HD_1773.
DR   KEGG; hdu:HD_1773; -.
DR   eggNOG; COG0823; Bacteria.
DR   HOGENOM; CLU_047123_0_0_6; -.
DR   OMA; VREPSWG; -.
DR   Proteomes; UP000001022; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 4.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           25..426
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_0000034655"
SQ   SEQUENCE   426 AA;  45611 MW;  F68574D20333C356 CRC64;
     MKLKSRYTSL ISVVSIFFSS MVMAESDIVI SVDEGVSIAQ PIAVVPFKVN GGVSEDVGQV
     VADDLRNSGK FTPIQRAKLP SHPASVAEIN SQQWTDIGVD VVVVGQITPA NNGYNVAYQL
     VDTLSNPAVV LVQGSFNVPA TQMRQAAHTV SDQIFEKLTQ IRGAFRTKIA YVVQRGVSAY
     ELRVADYDGF NAFTVVKSKE PLMSPEWSPN GSKLAYVTFE NKRPQIVVHD LRSGQRSVVA
     ALKGHNGAPA FSPDGSRLAF ASNQDGELNI YIANINGGTP IKLTANVGNN TEPSWSPDGS
     IIYFTSDRAG SPQVYRMSSS GNDVIPIGTR GSYNAKASSD GKNLIMIAGD NVVKQDLTSG
     STEVLSSTFL DESPSISPNG IMIIYSSTKG TSKVLQLVSA DGRFKANLPG AEGQFKFPAW
     SPYLTK