ID   TOLB_HAEI8              Reviewed;         427 AA.
AC   Q4QNG0;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=NTHI0502;
OS   Haemophilus influenzae (strain 86-028NP).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=281310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=86-028NP;
RX   PubMed=15968074; DOI=10.1128/jb.187.13.4627-4636.2005;
RA   Harrison A., Dyer D.W., Gillaspy A., Ray W.C., Mungur R., Carson M.B.,
RA   Zhong H., Gipson J., Gipson M., Johnson L.S., Lewis L., Bakaletz L.O.,
RA   Munson R.S. Jr.;
RT   "Genomic sequence of an otitis media isolate of nontypeable Haemophilus
RT   influenzae: comparative study with H. influenzae serotype d, strain KW20.";
RL   J. Bacteriol. 187:4627-4636(2005).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; CP000057; AAX87437.1; -; Genomic_DNA.
DR   RefSeq; WP_011272014.1; NC_007146.2.
DR   AlphaFoldDB; Q4QNG0; -.
DR   SMR; Q4QNG0; -.
DR   EnsemblBacteria; AAX87437; AAX87437; NTHI0502.
DR   KEGG; hit:NTHI0502; -.
DR   HOGENOM; CLU_047123_0_0_6; -.
DR   OMA; VREPSWG; -.
DR   OrthoDB; 821953at2; -.
DR   Proteomes; UP000002525; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 4.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           24..427
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_0000259051"
SQ   SEQUENCE   427 AA;  44938 MW;  088D810FEE964A09 CRC64;
     MKLLKRLVSV FAIVLAVGSN AFAGDEVRIV IDEGVDGARP IAVVPFVGSA PEDISKIVAD
     DLRNSGKFNP IAVSQMPQRP TSAAEVNPEA WSNIGIDAIV IGQVVPSGNG YSITYQLIDT
     VGASGTPGAV LMQNSYTVTN KWLRYGAHTV SDEVFEKLTA IRGAFRTRIA YVVQKNGGSQ
     PYEVRVADYD GYNQFIVNRS AQPIMSPAWS PDGQRLAYVS FENKKSQLVV QDLNSGARKV
     VASFQGHNGA PAFSPDGSRL AFASSRDGVL NIYVMGANGG TPTQLTSGAG NNTEPAWSPD
     GNSILFTSDR SGSPQVYRMD ASGGSATAVG GRGSAQISAD GKTLVMINGN NNVVKQDLTT
     GVSEVLSTSF LGESPSLSPN GIMIIYSSTQ GLGKVLQLVS ADGRFKASLP GSDGQVKFPA
     WSPYLTK