ID   TOLB_HAEIG              Reviewed;         427 AA.
AC   A5UGQ1;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671};
GN   OrderedLocusNames=CGSHiGG_05070;
OS   Haemophilus influenzae (strain PittGG).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=374931;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PittGG;
RX   PubMed=17550610; DOI=10.1186/gb-2007-8-6-r103;
RA   Hogg J.S., Hu F.Z., Janto B., Boissy R., Hayes J., Keefe R., Post J.C.,
RA   Ehrlich G.D.;
RT   "Characterization and modeling of the Haemophilus influenzae core and
RT   supragenomes based on the complete genomic sequences of Rd and 12 clinical
RT   nontypeable strains.";
RL   Genome Biol. 8:R103.1-R103.18(2007).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; CP000672; ABQ99956.1; -; Genomic_DNA.
DR   RefSeq; WP_012055002.1; NC_009567.1.
DR   AlphaFoldDB; A5UGQ1; -.
DR   SMR; A5UGQ1; -.
DR   EnsemblBacteria; ABQ99956; ABQ99956; CGSHiGG_05070.
DR   KEGG; hiq:CGSHiGG_05070; -.
DR   HOGENOM; CLU_047123_0_0_6; -.
DR   OMA; VREPSWG; -.
DR   Proteomes; UP000001990; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 4.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           24..427
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_1000026704"
SQ   SEQUENCE   427 AA;  44992 MW;  EDB7EB65C193709A CRC64;
     MKLLKRLVSV FAIVLAVGSN AFAGDEVRIV IDEGVDGARP IAVVPFVGSA PEDISKIVAD
     DLRNSGKFNP IAVSQMPQHP TSAAEVNPEA WSNIGIDAIV IGQVVPSGNG YSITYQLIDT
     VGASGTPGTV LMQNSYTVTN KWLRYGAHTV SDEVFEKLTA IRGAFRTRIA YVVQKNGGSQ
     PYEVRVADYD GYNQFIVNRS AQPIMSPAWS PDGQRLAYVS FENKKSQLVV QDLNSGSRKV
     VASFQGHNGA PAFSPDGSRL AFASSRDGVL NIYVMGANGG TPTQLTSGAG NNTEPAWSPD
     GNSILFTSDR SGSPQVYRMD ASGGNATAVG GRGSAQISAD GKTLVMINGN NNVVKQDLTT
     GVSEVLSTSF LGESPSLSPN GIMIIYSSTQ GLGKVLQLVS ADGRFKASLP GSDGQVKFPA
     WSPYLTK