TOLB_HAEIG
ID TOLB_HAEIG Reviewed; 427 AA.
AC A5UGQ1;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 10-JUL-2007, sequence version 1.
DT 25-MAY-2022, entry version 75.
DE RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE Flags: Precursor;
GN Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671};
GN OrderedLocusNames=CGSHiGG_05070;
OS Haemophilus influenzae (strain PittGG).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=374931;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PittGG;
RX PubMed=17550610; DOI=10.1186/gb-2007-8-6-r103;
RA Hogg J.S., Hu F.Z., Janto B., Boissy R., Hayes J., Keefe R., Post J.C.,
RA Ehrlich G.D.;
RT "Characterization and modeling of the Haemophilus influenzae core and
RT supragenomes based on the complete genomic sequences of Rd and 12 clinical
RT nontypeable strains.";
RL Genome Biol. 8:R103.1-R103.18(2007).
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000672; ABQ99956.1; -; Genomic_DNA.
DR RefSeq; WP_012055002.1; NC_009567.1.
DR AlphaFoldDB; A5UGQ1; -.
DR SMR; A5UGQ1; -.
DR EnsemblBacteria; ABQ99956; ABQ99956; CGSHiGG_05070.
DR KEGG; hiq:CGSHiGG_05070; -.
DR HOGENOM; CLU_047123_0_0_6; -.
DR OMA; VREPSWG; -.
DR Proteomes; UP000001990; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR Gene3D; 2.120.10.30; -; 1.
DR HAMAP; MF_00671; TolB; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR014167; Tol-Pal_TolB.
DR InterPro; IPR007195; TolB_N.
DR Pfam; PF07676; PD40; 4.
DR Pfam; PF04052; TolB_N; 1.
DR TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Periplasm; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT CHAIN 24..427
FT /note="Tol-Pal system protein TolB"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT /id="PRO_1000026704"
SQ SEQUENCE 427 AA; 44992 MW; EDB7EB65C193709A CRC64;
MKLLKRLVSV FAIVLAVGSN AFAGDEVRIV IDEGVDGARP IAVVPFVGSA PEDISKIVAD
DLRNSGKFNP IAVSQMPQHP TSAAEVNPEA WSNIGIDAIV IGQVVPSGNG YSITYQLIDT
VGASGTPGTV LMQNSYTVTN KWLRYGAHTV SDEVFEKLTA IRGAFRTRIA YVVQKNGGSQ
PYEVRVADYD GYNQFIVNRS AQPIMSPAWS PDGQRLAYVS FENKKSQLVV QDLNSGSRKV
VASFQGHNGA PAFSPDGSRL AFASSRDGVL NIYVMGANGG TPTQLTSGAG NNTEPAWSPD
GNSILFTSDR SGSPQVYRMD ASGGNATAVG GRGSAQISAD GKTLVMINGN NNVVKQDLTT
GVSEVLSTSF LGESPSLSPN GIMIIYSSTQ GLGKVLQLVS ADGRFKASLP GSDGQVKFPA
WSPYLTK