BTN1_CHAGB
ID BTN1_CHAGB Reviewed; 459 AA.
AC Q2GN49;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 21-MAR-2006, sequence version 1.
DT 25-MAY-2022, entry version 60.
DE RecName: Full=Protein BTN1;
GN Name=BTN1; ORFNames=CHGG_10605;
OS Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS NRRL 1970) (Soil fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX NCBI_TaxID=306901;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970;
RX PubMed=25720678; DOI=10.1128/genomea.00021-15;
RA Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL Genome Announc. 3:E0002115-E0002115(2015).
CC -!- FUNCTION: Involved in vacuolar transport and vacuole pH homeostasis.
CC Also required for cytokinesis (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the battenin family. {ECO:0000305}.
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DR EMBL; CH408035; EAQ84201.1; -; Genomic_DNA.
DR RefSeq; XP_001228532.1; XM_001228531.1.
DR AlphaFoldDB; Q2GN49; -.
DR STRING; 38033.XP_001228532.1; -.
DR EnsemblFungi; EAQ84201; EAQ84201; CHGG_10605.
DR GeneID; 4396522; -.
DR eggNOG; KOG3880; Eukaryota.
DR HOGENOM; CLU_029663_1_2_1; -.
DR InParanoid; Q2GN49; -.
DR OMA; WLCNWQV; -.
DR OrthoDB; 1037817at2759; -.
DR Proteomes; UP000001056; Unassembled WGS sequence.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR003492; Battenin_disease_Cln3.
DR InterPro; IPR018460; Battenin_disease_Cln3_subgr.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR10981; PTHR10981; 1.
DR Pfam; PF02487; CLN3; 1.
DR PIRSF; PIRSF015974; CLN3_BTN1; 1.
DR PRINTS; PR01315; BATTENIN.
DR SUPFAM; SSF103473; SSF103473; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport; Vacuole.
FT CHAIN 1..459
FT /note="Protein BTN1"
FT /id="PRO_0000256259"
FT TRANSMEM 37..57
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 102..122
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 129..149
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 167..187
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 189..209
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 240..260
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 283..303
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 325..342
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 352..372
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 374..394
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 459 AA; 49227 MW; ECE0823B74249770 CRC64;
MNRSPSTSGL LPLPGTPSSS WALYRARLSN MFRNTDVSVV IAFWLFGLIN NILYVLVLSA
AQDLVGTSVP KGAVLLADVL PSFLTKLVAP YFIHRVPYSV RIAVFVALSC AGMLVVAAAP
VEGAVGVKLL GVVLASLSSG GGELSFLGLT HYYGHGSLAA WGSGTGGAGL VGAGLYVVLT
GWIGLGVRGS LLVGALLPSV MVVAFWGILP RGPLKGWKGG YERVAEPGEE EDGEEGFEDV
PAGAASAGLL APGPSVAATA YTHHHEGRTG RASFWGNVRR ARALFFPYML PLLLVYVAEY
TINQGVAPTL LFPLDQSPFS EFREYYPFYG FLYQLGVFIS RSSTPFIRIH HLYLPSFLQV
ANLVLLTLHA VLNFIPSVYL VFVVIFWEGL LGGAVYVNTF AEIMENVPAE DREFSLGATS
VSDSGGICIA GFLGMAMEVW LCRWQVSQGR DYCRRIEAS
