ID   TOLB_HELHP              Reviewed;         419 AA.
AC   Q7VJ16;
DT   07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=HH_0434;
OS   Helicobacter hepaticus (strain ATCC 51449 / 3B1).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=235279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51449 / 3B1;
RX   PubMed=12810954; DOI=10.1073/pnas.1332093100;
RA   Suerbaum S., Josenhans C., Sterzenbach T., Drescher B., Brandt P., Bell M.,
RA   Droege M., Fartmann B., Fischer H.-P., Ge Z., Hoerster A., Holland R.,
RA   Klein K., Koenig J., Macko L., Mendz G.L., Nyakatura G., Schauer D.B.,
RA   Shen Z., Weber J., Frosch M., Fox J.G.;
RT   "The complete genome sequence of the carcinogenic bacterium Helicobacter
RT   hepaticus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7901-7906(2003).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; AE017125; AAP77031.1; -; Genomic_DNA.
DR   RefSeq; WP_011115276.1; NC_004917.1.
DR   AlphaFoldDB; Q7VJ16; -.
DR   SMR; Q7VJ16; -.
DR   STRING; 235279.HH_0434; -.
DR   EnsemblBacteria; AAP77031; AAP77031; HH_0434.
DR   KEGG; hhe:HH_0434; -.
DR   eggNOG; COG0823; Bacteria.
DR   HOGENOM; CLU_665280_0_0_7; -.
DR   OMA; DIYGPGQ; -.
DR   OrthoDB; 821953at2; -.
DR   Proteomes; UP000002495; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF04052; TolB_N; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           18..419
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_0000034657"
SQ   SEQUENCE   419 AA;  47264 MW;  5D4C1581855E13E2 CRC64;
     MRFIGLVLLL LSVKLFGIDA TLEIVKNTNK IPYIVVERLD SENADFGAKV LKMLAADLKV
     SGHFQVYDGS VNKNSEVAYK DYADKKIDLL AQIKVSKSSN SLTGTISLYD INTSKRIYVK
     DYTENDVKRF PFIAHRMCID VNSYIQAPSI EWMQRLVVLS QYTTSGNSEI LIADYTLTYQ
     KVVVKGGLNI FPKWVDSKQE SIYYTKYLDV PTILKHNLTT GHIEQLVGSE GIAVVSDVSK
     NGENLILSLS PTALSDLYLY NTKSKNLRRL TNYSGIDVDG KFVNNEKEII FVSDRLGYPN
     IFMMRLDGGG TEQVVLHGRN NSAVTSNGKY AVYTSRETNN EFGANTFNLY LISLAPGSNY
     IRRLTASGKN QMPKYSNDGG TIMYLKYYKA QSALGIIRID YNTNYFFPLI KMKIQAFDW