ID   TOLB_HELPH              Reviewed;         417 AA.
AC   Q1CSE0;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=HPAG1_1065;
OS   Helicobacter pylori (strain HPAG1).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=357544;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HPAG1;
RX   PubMed=16788065; DOI=10.1073/pnas.0603784103;
RA   Oh J.D., Kling-Baeckhed H., Giannakis M., Xu J., Fulton R.S., Fulton L.A.,
RA   Cordum H.S., Wang C., Elliott G., Edwards J., Mardis E.R., Engstrand L.G.,
RA   Gordon J.I.;
RT   "The complete genome sequence of a chronic atrophic gastritis Helicobacter
RT   pylori strain: evolution during disease progression.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:9999-10004(2006).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; CP000241; ABF85132.1; -; Genomic_DNA.
DR   RefSeq; WP_001269988.1; NC_008086.1.
DR   AlphaFoldDB; Q1CSE0; -.
DR   SMR; Q1CSE0; -.
DR   EnsemblBacteria; ABF85132; ABF85132; HPAG1_1065.
DR   KEGG; hpa:HPAG1_1065; -.
DR   HOGENOM; CLU_665280_0_0_7; -.
DR   OMA; DIYGPGQ; -.
DR   OrthoDB; 821953at2; -.
DR   Proteomes; UP000008835; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   Pfam; PF07676; PD40; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           17..417
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_0000259053"
SQ   SEQUENCE   417 AA;  47708 MW;  5146A2A7F730F952 CRC64;
     MRYLWLFLIG TIGLFATDKT LDIIKTIQKL PKIEVRYSTD NDANYALKLH EVLANDLKTS
     QHFDVSQNKD QGAINYTELK DKKVHLVALV SVAVENGNKI SRLKLYDVNT STLVKTFDYP
     ILSADLYPFA AHNMAIVVND YLKAPSIAWM KRLIVFSKYI GPGITNIALA DYTMRYQKEI
     IKNNRLNIFP KWANAEQTEF YYTQYGERTP MILKYNIQKA THENIASSQG MAVVSSVSSD
     GSKILMSLAP DGQPDVYLYD THKKTKTKIT RYPGIDVSGV FLEDDKSMAF VSDRSGYPNI
     YMKKLGLKES AEQLLYEGRS NESIDAYKDS IVYVSRENLN EFGKTVFNLN LITLNSKYIR
     RLTVNGSNQM PRFSTDGRNI MYIKKTPQEY AMGLILLDYN QSFLFPLKNV KIQAFDW