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TOLB_HELPJ
ID   TOLB_HELPJ              Reviewed;         417 AA.
AC   Q9ZK86;
DT   11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 107.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=jhp_1055;
OS   Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J99 / ATCC 700824;
RX   PubMed=9923682; DOI=10.1038/16495;
RA   Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA   Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J.,
RA   Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D.,
RA   Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J.;
RT   "Genomic sequence comparison of two unrelated isolates of the human gastric
RT   pathogen Helicobacter pylori.";
RL   Nature 397:176-180(1999).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; AE001439; AAD06634.1; -; Genomic_DNA.
DR   PIR; G71854; G71854.
DR   RefSeq; WP_000876455.1; NZ_CP011330.1.
DR   AlphaFoldDB; Q9ZK86; -.
DR   SMR; Q9ZK86; -.
DR   STRING; 85963.jhp_1055; -.
DR   EnsemblBacteria; AAD06634; AAD06634; jhp_1055.
DR   KEGG; hpj:jhp_1055; -.
DR   PATRIC; fig|85963.30.peg.1533; -.
DR   eggNOG; COG0823; Bacteria.
DR   OMA; DIYGPGQ; -.
DR   Proteomes; UP000000804; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   Pfam; PF07676; PD40; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           17..417
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_0000034659"
SQ   SEQUENCE   417 AA;  47742 MW;  25FCF032F0ECE917 CRC64;
     MKYLWLFLIY AIGLFATDKT LDIIKTIQKL PKIEVRYSID NDANYALKLH EVLANDLKTS
     QHFDVSQNKE QGAINYAELK DKKVHLVALV SVAVENGNKI SRLKLYDVDT GTLKKTFDYP
     IVSLDLYPFA AHNMAIVVND YLKAPSIAWM KRLIVFSKYI GPGITNIALA DYTMRYQKEI
     IKNNRLNIFP KWANAEQTEF YYTQYGEKTP MILKYNIQKA THENIASSQG MAVVSSVSSD
     GSKILMSLAP DGQPDVYLYD THKKTKTKIT RYPGIDVSGV FLEDDKSMAF VSDRSGYPNI
     YMKKLGLKES AEQLLYEGRS NESIDAYKDS IVYVSRENLN EFGKTVFNLN LIALNSKYIR
     RLTVNGSNQM PRFSMDGRNI MYIKKTSQEY AMGLILLDYN QSFLFPLKNV KIQAFDW
 
 
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