ID   TOLB_HISS2              Reviewed;         434 AA.
AC   B0UVJ6;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=HSM_0135;
OS   Histophilus somni (strain 2336) (Haemophilus somnus).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Histophilus.
OX   NCBI_TaxID=228400;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2336;
RG   US DOE Joint Genome Institute;
RA   Siddaramappa S., Duncan A.J., Challacombe J.F., Rainey D., Gillaspy A.F.,
RA   Carson M., Gipson J., Gipson M., Bruce D., Detter J.C., Han C.S., Land M.,
RA   Tapia R., Thompson L.S., Orvis J., Zaitshik J., Barnes G., Brettin T.S.,
RA   Dyer D.W., Inzana T.J.;
RT   "Complete sequence of Haemophilus somnus 2336.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000947; ACA31085.1; -; Genomic_DNA.
DR   RefSeq; WP_012340504.1; NC_010519.1.
DR   AlphaFoldDB; B0UVJ6; -.
DR   SMR; B0UVJ6; -.
DR   STRING; 228400.HSM_0135; -.
DR   EnsemblBacteria; ACA31085; ACA31085; HSM_0135.
DR   KEGG; hsm:HSM_0135; -.
DR   HOGENOM; CLU_047123_0_0_6; -.
DR   OMA; VREPSWG; -.
DR   OrthoDB; 821953at2; -.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 4.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           25..434
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_5000311140"
SQ   SEQUENCE   434 AA;  46356 MW;  D0E627B336605561 CRC64;
     MKFSAYLTTL FIVLFSLFIQ TVQAESEVRI VIDEGVDSAR PIAIIPFKWN GSDSMPIDVA
     DIISADLRNS GKFNPIAVSK MPQKPTSASE VISDVWSSLG IDAVVVGQVT PNEKGYSIAY
     QLVDTIGASG NSGEVLSQNQ YAVPKNAIRL GAHTISDEVF EKLTAIRGAF RTKIAYVVQK
     NGGSKPYQVR IADYDGHNQF IVYSSSQPLM SPAWSPDGSK LAYVSFENRK SQLIVHDLQS
     GARRVIAAFP GHNGAPAFSP DGSKIAFASS KDGVLNIYVM NLGNGTISQL TSGAGNNTEP
     SWSPDGQSII FTSDRAGGPQ IYQMDVVGNG VSLVSAGRGY SGKISADGSI LVMIYGDNIV
     KKDLATGVTE MLSSTFLDES PSISPNGIMI IYSSTQGLGK VLQLVSADGR FKARLPSSDG
     QIKFPAWSPY LNKN