TOLB_MANSM
ID TOLB_MANSM Reviewed; 431 AA.
AC Q65UN0;
DT 07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2004, sequence version 1.
DT 25-MAY-2022, entry version 93.
DE RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE Flags: Precursor;
GN Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=MS0723;
OS Mannheimia succiniciproducens (strain MBEL55E).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Basfia.
OX NCBI_TaxID=221988;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MBEL55E;
RX PubMed=15378067; DOI=10.1038/nbt1010;
RA Hong S.H., Kim J.S., Lee S.Y., In Y.H., Choi S.S., Rih J.-K., Kim C.H.,
RA Jeong H., Hur C.G., Kim J.J.;
RT "The genome sequence of the capnophilic rumen bacterium Mannheimia
RT succiniciproducens.";
RL Nat. Biotechnol. 22:1275-1281(2004).
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
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DR EMBL; AE016827; AAU37330.1; -; Genomic_DNA.
DR AlphaFoldDB; Q65UN0; -.
DR SMR; Q65UN0; -.
DR STRING; 221988.MS0723; -.
DR EnsemblBacteria; AAU37330; AAU37330; MS0723.
DR KEGG; msu:MS0723; -.
DR eggNOG; COG0823; Bacteria.
DR HOGENOM; CLU_047123_0_0_6; -.
DR OMA; VREPSWG; -.
DR Proteomes; UP000000607; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR Gene3D; 2.120.10.30; -; 1.
DR HAMAP; MF_00671; TolB; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR014167; Tol-Pal_TolB.
DR InterPro; IPR007195; TolB_N.
DR Pfam; PF07676; PD40; 4.
DR Pfam; PF04052; TolB_N; 1.
DR TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Periplasm; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT CHAIN 25..431
FT /note="Tol-Pal system protein TolB"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT /id="PRO_0000034664"
FT REGION 318..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 431 AA; 45147 MW; 7FA417AC4711D2E8 CRC64;
MMKFLTRMLS AFAVLFFAIS TAQADDEVRI VIDEGVDGAR PIAVVPFKTN GSVPADIAEI
VTADLRNSGK FNPIPVSQMP QQPASASEVT PDAWAALGVD AIVVGQVTAT GNGYNIAYQL
VDTVGASGGA GAVLAQNSVT VGAKWIRYGA HTVSDEVFEK LTAIKGAFRT RIAYVVQKNG
GSKPYEIRVA DYDGFNQFIV NRSSQPIMSP AWSPDGKRLA YVSFENRKSQ LVVQDLGSGA
RKVVASFQGH NGAPAFSPDG SRLAFASNKE GQLNIYVMGA NGGQPTQLTS GSGNNTEPSW
SPDGSSILFT SDRGGSPQVY RMSSSGGAAS PVGGRGSAQI SSDGKTLVMI NGNNNVVKQD
VTSGASEVLS TSFLGESPSL SPNGIMIIYS STQGLGKVLQ LVSADGRFKA RLPGTDGQVK
FPAWSPYLDK N