TOLB_NITWN
ID TOLB_NITWN Reviewed; 450 AA.
AC Q3SP21;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 25-MAY-2022, entry version 108.
DE RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE Flags: Precursor;
GN Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=Nwi_2717;
OS Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 /
OS NCIMB 11846 / Nb-255).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Bradyrhizobiaceae; Nitrobacter.
OX NCBI_TaxID=323098;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255;
RX PubMed=16517654; DOI=10.1128/aem.72.3.2050-2063.2006;
RA Starkenburg S.R., Chain P.S.G., Sayavedra-Soto L.A., Hauser L., Land M.L.,
RA Larimer F.W., Malfatti S.A., Klotz M.G., Bottomley P.J., Arp D.J.,
RA Hickey W.J.;
RT "Genome sequence of the chemolithoautotrophic nitrite-oxidizing bacterium
RT Nitrobacter winogradskyi Nb-255.";
RL Appl. Environ. Microbiol. 72:2050-2063(2006).
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000115; ABA05970.1; -; Genomic_DNA.
DR AlphaFoldDB; Q3SP21; -.
DR SMR; Q3SP21; -.
DR STRING; 323098.Nwi_2717; -.
DR EnsemblBacteria; ABA05970; ABA05970; Nwi_2717.
DR KEGG; nwi:Nwi_2717; -.
DR eggNOG; COG0823; Bacteria.
DR HOGENOM; CLU_047123_0_0_5; -.
DR OMA; VREPSWG; -.
DR Proteomes; UP000002531; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR Gene3D; 2.120.10.30; -; 1.
DR HAMAP; MF_00671; TolB; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR014167; Tol-Pal_TolB.
DR InterPro; IPR007195; TolB_N.
DR Pfam; PF07676; PD40; 4.
DR Pfam; PF04052; TolB_N; 1.
DR TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Periplasm; Reference proteome; Signal.
FT SIGNAL 1..37
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT CHAIN 38..450
FT /note="Tol-Pal system protein TolB"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT /id="PRO_0000259060"
SQ SEQUENCE 450 AA; 49097 MW; C1FC61D89E6EEA15 CRC64;
MIERNGLQRM PFRLNRRHMI SGMASAAVLL GSRQALGQAR VQITEGNVAP LPIAIPNFVG
GTPSDNEVGA GVAKVITNNL KRSGLFAPID QAAYIEKITN IDVPPQFANW KTINAQALVT
GRMTRQGDGR LKAEFRLWDV ATGQQLAGQQ YFTSPEYWRR IAHIISDQIY ERLTGEKGYF
DSRVVFVDES GSSQRRVKRL ALMDQDGANV RYLTRGADLV ITPRFSPSTQ EVTYMEFGQG
DPRVYLFNIE TGQREIVGNF PGMSFSPRFA PDGQRIIMSL QQGGNSNLFV MDLRSKSTTR
LTDTPAIDTS PSYSPDGARI CFESDRGGKP QIYVMGATGG GAQRISFGEG SYSTPVWSPR
GDYIAFTKQG GGQFSIGIIK PDGSGERILT SGFHNEGPTF APNGRVLMFF RDPGGGGGPS
LYTIDVSGRN ELKVPTPGFA SDPAWSPLLS