ID   TOLB_ORITB              Reviewed;         453 AA.
AC   A5CBX4;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=OTBS_0018;
OS   Orientia tsutsugamushi (strain Boryong) (Rickettsia tsutsugamushi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Orientia.
OX   NCBI_TaxID=357244;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Boryong;
RX   PubMed=17483455; DOI=10.1073/pnas.0611553104;
RA   Cho N.-H., Kim H.-R., Lee J.-H., Kim S.-Y., Kim J., Cha S., Kim S.-Y.,
RA   Darby A.C., Fuxelius H.-H., Yin J., Kim J.H., Kim J., Lee S.J., Koh Y.-S.,
RA   Jang W.-J., Park K.-H., Andersson S.G.E., Choi M.-S., Kim I.-S.;
RT   "The Orientia tsutsugamushi genome reveals massive proliferation of
RT   conjugative type IV secretion system and host-cell interaction genes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:7981-7986(2007).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; AM494475; CAM79084.1; -; Genomic_DNA.
DR   RefSeq; WP_011944239.1; NC_009488.1.
DR   AlphaFoldDB; A5CBX4; -.
DR   SMR; A5CBX4; -.
DR   EnsemblBacteria; CAM79084; CAM79084; OTBS_0018.
DR   KEGG; ots:OTBS_0018; -.
DR   eggNOG; COG0823; Bacteria.
DR   HOGENOM; CLU_047123_0_0_5; -.
DR   OMA; WLPNGRE; -.
DR   Proteomes; UP000001565; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 4.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..31
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           32..453
FT                   /note="Tol-Pal system protein TolB"
FT                   /id="PRO_1000131532"
SQ   SEQUENCE   453 AA;  50377 MW;  A9E0F90AA664D650 CRC64;
     MINNLSVSMT KVLKIILTII IILFNTLSIL ANTTTLSSIK ITKGNCTQIP IAINFFSAKS
     NEEHDLSQNI VSIISNDLNI SKIFAPISSD LFIETEQGVA HIPLFTAWSQ INANILINGE
     ITKIDSTDFK VTFVIWDVFS AKEITRKSFT FPSQLWRSTA HKIADQIYKH VTGSKGNFNT
     KIVYVSESNS SNRKIRRIAI MDQDGANHNY ITNGKNHVIT PVFSPKNNQI LYVSYHNKIP
     TVRIHDLNSG NNKILASFNG ITFSPRFSPD GNKILVSNSS TKNVTHIYEI NLLTGKIKQL
     TKGQSINTSP SYSPDGSKIA FVSDRSGSTQ IYIMNDQGGN IKRLTSQPGA YTTPAWSPTN
     NYIAFTKIEA GEFSIGVIKL DGSNKRIIAT KYLVEGPSWA PDGKTIIFSR AYKATKSTST
     KVKLYSVDYT GYNEREIQTP ENASDPNWSN EYE