ID   TOLB_ORITI              Reviewed;         453 AA.
AC   B3CUF6;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   22-JUL-2008, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=OTT_1545;
OS   Orientia tsutsugamushi (strain Ikeda) (Rickettsia tsutsugamushi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Orientia.
OX   NCBI_TaxID=334380;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ikeda;
RX   PubMed=18508905; DOI=10.1093/dnares/dsn011;
RA   Nakayama K., Yamashita A., Kurokawa K., Morimoto T., Ogawa M., Fukuhara M.,
RA   Urakami H., Ohnishi M., Uchiyama I., Ogura Y., Ooka T., Oshima K.,
RA   Tamura A., Hattori M., Hayashi T.;
RT   "The whole-genome sequencing of the obligate intracellular bacterium
RT   Orientia tsutsugamushi revealed massive gene amplification during reductive
RT   genome evolution.";
RL   DNA Res. 15:185-199(2008).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; AP008981; BAG41003.1; -; Genomic_DNA.
DR   RefSeq; WP_012462010.1; NC_010793.1.
DR   AlphaFoldDB; B3CUF6; -.
DR   SMR; B3CUF6; -.
DR   PRIDE; B3CUF6; -.
DR   EnsemblBacteria; BAG41003; BAG41003; OTT_1545.
DR   GeneID; 66653460; -.
DR   KEGG; ott:OTT_1545; -.
DR   HOGENOM; CLU_047123_0_0_5; -.
DR   OMA; WLPNGRE; -.
DR   OrthoDB; 821953at2; -.
DR   Proteomes; UP000001033; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 5.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Signal.
FT   SIGNAL          1..31
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           32..453
FT                   /note="Tol-Pal system protein TolB"
FT                   /id="PRO_1000131533"
SQ   SEQUENCE   453 AA;  50132 MW;  435AAD080F8279E2 CRC64;
     MINNLSISMT KVIKIILAII IILFNTLSIF ANTTTLSPIK ITKGNCTQIP IAINFFAAKS
     NEEHGLSQNI VSIISNDLNI SKIFAPISSD LFIETEQGVA HIPLFTAWSQ INANILINGE
     ITKIDSTDFK VTFVVWDVFS AKEITRKSFT FPSQLWRSTA HKIADQIYKH VTGSKGNFNT
     KIVYVSESNS SKGKIRRIAI MDQDGANHNY ITNGKNHVIT PVFSPNNNQI LYVSYHNKIP
     TVRIHDLNSG NNKILASFNG ITFSPRFSPD GNKILVSNSS TKNVTHIYEI NLLTGKIKQL
     TKGQSINTSP SYSPDGSKIA FVSDRSGSTQ IYIMNDQGGN IKRLTSQPGA YTTPAWSPTN
     NYIAFTKIEA GEFSIGVIKL DGSNKRIIAT KHLVEGPSWA PDGKTIIFSR AYKATKSTST
     KVKLYSVDCT GYNEREIQTP ENASDPNWSN EYE