TOLB_PARL1
ID TOLB_PARL1 Reviewed; 446 AA.
AC A7HV03;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-SEP-2007, sequence version 1.
DT 25-MAY-2022, entry version 75.
DE RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE Flags: Precursor;
GN Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=Plav_2122;
OS Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Parvibaculaceae; Parvibaculum.
OX NCBI_TaxID=402881;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS-1 / DSM 13023 / NCIMB 13966;
RX PubMed=22675581; DOI=10.4056/sigs.2215005;
RA Schleheck D., Weiss M., Pitluck S., Bruce D., Land M.L., Han S.,
RA Saunders E., Tapia R., Detter C., Brettin T., Han J., Woyke T., Goodwin L.,
RA Pennacchio L., Nolan M., Cook A.M., Kjelleberg S., Thomas T.;
RT "Complete genome sequence of Parvibaculum lavamentivorans type strain (DS-
RT 1(T)).";
RL Stand. Genomic Sci. 5:298-310(2011).
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
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DR EMBL; CP000774; ABS63736.1; -; Genomic_DNA.
DR AlphaFoldDB; A7HV03; -.
DR SMR; A7HV03; -.
DR STRING; 402881.Plav_2122; -.
DR PRIDE; A7HV03; -.
DR EnsemblBacteria; ABS63736; ABS63736; Plav_2122.
DR KEGG; pla:Plav_2122; -.
DR eggNOG; COG0823; Bacteria.
DR HOGENOM; CLU_047123_0_0_5; -.
DR OMA; VREPSWG; -.
DR Proteomes; UP000006377; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR Gene3D; 2.120.10.30; -; 1.
DR HAMAP; MF_00671; TolB; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR014167; Tol-Pal_TolB.
DR InterPro; IPR007195; TolB_N.
DR Pfam; PF07676; PD40; 3.
DR Pfam; PF04052; TolB_N; 1.
DR TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Periplasm; Reference proteome; Signal.
FT SIGNAL 1..36
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT CHAIN 37..446
FT /note="Tol-Pal system protein TolB"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT /id="PRO_5000267631"
FT REGION 424..446
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..439
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 446 AA; 49575 MW; 90530D6D202A9B47 CRC64;
MMDVQTVRRG NAVQSLMSKL ILPLVMAVAF ALPARAALQI DITQGNVDPL PIAITDFVGE
GSVGADMSAV ISNNLERSGL FRPLPKASFI EKVSDINVQP RFGDWRVINS QALVTGQTRM
EADGRLRVEF RLWDVLGEQQ LTGLQFFTTP DNWRRVAHLI SDAIYKRLTG EDGYFDTRIV
YVSETGPKNA RVKRLTIMDQ DGHNPRMLTR GNELVLTPRF SPNSQEITYL AYRNNQPRVY
VLDIETGQQE VVGEFPGMTF APRFSPDGQR IIMSLQRGGN SDIYTMDLRS RQVVRLTNTA
AIDTAPSYSP DGRQITFESD RGGSQQIYVM DASGSNQRRI SFGQGSYATP VWSPRGDLIA
FTKITGGRFV IGVMRPDGTG ERVLTDGFHN EGPTWAPNGR VLMFFRETRG AQGGPSLWSV
DVTGYNERPS PTPTFASDPA WSPRIQ