ID   TOLB_PELUB              Reviewed;         446 AA.
AC   Q4FN21;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   30-AUG-2005, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=SAR11_0597;
OS   Pelagibacter ubique (strain HTCC1062).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Pelagibacterales;
OC   Pelagibacteraceae; Candidatus Pelagibacter.
OX   NCBI_TaxID=335992;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTCC1062;
RX   PubMed=16109880; DOI=10.1126/science.1114057;
RA   Giovannoni S.J., Tripp H.J., Givan S., Podar M., Vergin K.L., Baptista D.,
RA   Bibbs L., Eads J., Richardson T.H., Noordewier M., Rappe M.S., Short J.M.,
RA   Carrington J.C., Mathur E.J.;
RT   "Genome streamlining in a cosmopolitan oceanic bacterium.";
RL   Science 309:1242-1245(2005).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; CP000084; AAZ21418.1; -; Genomic_DNA.
DR   RefSeq; WP_006997307.1; NC_007205.1.
DR   AlphaFoldDB; Q4FN21; -.
DR   SMR; Q4FN21; -.
DR   STRING; 335992.SAR11_0597; -.
DR   EnsemblBacteria; AAZ21418; AAZ21418; SAR11_0597.
DR   GeneID; 66295102; -.
DR   KEGG; pub:SAR11_0597; -.
DR   eggNOG; COG0823; Bacteria.
DR   HOGENOM; CLU_047123_0_0_5; -.
DR   OMA; VREPSWG; -.
DR   OrthoDB; 821953at2; -.
DR   Proteomes; UP000002528; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 3.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           20..446
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_0000259065"
SQ   SEQUENCE   446 AA;  50788 MW;  2EFE545673AE5459 CRC64;
     MLLRYLFILF IIIPIKAFAL IEVDITRGNL NPLPVAVSPL SIDNKSKENF KKILKQEDLG
     SEISIVVENN LRQSGLFNPL DKNAFLQEPD VANLKPRFED WNLIKAQALV TGKVTFVDEK
     LRVEFRLWDV LAGKEMMALA FTTVPSNWRR VGHIITDKVY ERLTGEKGYF DTRIIYVSEE
     GPKTKRIKKL AIMDQDGFNN KYLTLGNELV LTPRFSPTNQ MVTYLSYFRN LPRVYLLDIE
     TGMQEVVGDF PGMTFAPRFS PDGKKIIMSF AKDGNSDIYT MDLENRIVER ITNHPSIDTS
     PSYSPDGKKI TFNSDRSGYQ QIYVMDSNGK NVKRISFGNG LYGTPVWSPR GDLIAFTKLH
     KGKFYIGVMR TDGTGERLLT ENFYQEAPSW SPNGRVLIFY RETKTNSKGE GFSAKLWSID
     LTGYNEKMVE TETDASDPSW SSLLSN