TOLB_RICRO
ID TOLB_RICRO Reviewed; 444 AA.
AC B0BWZ3;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 26-FEB-2008, sequence version 1.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE Flags: Precursor;
GN Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=RrIowa_0487;
OS Rickettsia rickettsii (strain Iowa).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX NCBI_TaxID=452659;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Iowa;
RX PubMed=18025092; DOI=10.1128/iai.00952-07;
RA Ellison D.W., Clark T.R., Sturdevant D.E., Virtaneva K., Porcella S.F.,
RA Hackstadt T.;
RT "Genomic comparison of virulent Rickettsia rickettsii Sheila Smith and
RT avirulent Rickettsia rickettsii Iowa.";
RL Infect. Immun. 76:542-550(2008).
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
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DR EMBL; CP000766; ABY72369.1; -; Genomic_DNA.
DR RefSeq; WP_012262306.1; NC_010263.3.
DR AlphaFoldDB; B0BWZ3; -.
DR SMR; B0BWZ3; -.
DR STRING; 452659.RrIowa_0487; -.
DR EnsemblBacteria; ABY72369; ABY72369; RrIowa_0487.
DR GeneID; 45538994; -.
DR KEGG; rrj:RrIowa_0487; -.
DR eggNOG; COG0823; Bacteria.
DR HOGENOM; CLU_047123_0_0_5; -.
DR OMA; VREPSWG; -.
DR Proteomes; UP000000796; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR Gene3D; 2.120.10.30; -; 1.
DR HAMAP; MF_00671; TolB; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR014167; Tol-Pal_TolB.
DR InterPro; IPR007195; TolB_N.
DR Pfam; PF07676; PD40; 4.
DR Pfam; PF04052; TolB_N; 1.
DR TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Periplasm; Signal.
FT SIGNAL 1..19
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT CHAIN 20..444
FT /note="Tol-Pal system protein TolB"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT /id="PRO_1000082942"
SQ SEQUENCE 444 AA; 49151 MW; D7961C49FF575335 CRC64;
MRNIIYFILS LLFSVTSYAL ETINIEHGRA DPTPIAVNKF YADNSAADVL GHDMVKVISN
DLKLSGLFRP ISAASFIEEK TGIEYKPLFA AWRQINASLL VNGEVKKLES GKFQISFILW
DTLLEKQLVG EILEVPKNLW RRAAHKIADK IYEKITGDAG YFDTKIVYVS ESSSLPKIKR
IALMDYDGAN NKYLTNGKSL VLTPRFARSA DKIFYVSYAT KRRVLVYEKD LKTGKESVVG
DFPGISFAPR FSPDGRKAVM SIAKNGSTHI YEIDLATKRL HKLTDGFGIN TSPSYSPDGT
KIVYNSDRNG VPQLYIMNSD GSDVQRISFG GGSYAAPSWS PRGDYIAFTK ITKGDGGKTF
NIGIMKACPQ DNKNSERIIT SGYLVESPCW SPNGRVIMFA KGWPSSAKAP GKNKIFAIDL
TGHNEREIMT PADASDPEWS GVLN