BTN1_USTMA
ID BTN1_USTMA Reviewed; 545 AA.
AC Q4P4U7; A0A0D1BY42;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 16-SEP-2015, sequence version 2.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Protein BTN1;
GN Name=BTN1; ORFNames=UMAG_10856;
OS Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX NCBI_TaxID=237631;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=521 / FGSC 9021;
RX PubMed=17080091; DOI=10.1038/nature05248;
RA Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA Birren B.W.;
RT "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT maydis.";
RL Nature 444:97-101(2006).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=521 / FGSC 9021;
RA Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in vacuolar transport and vacuole pH homeostasis.
CC Also required for cytokinesis (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the battenin family. {ECO:0000305}.
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DR EMBL; CM003156; KIS66807.1; -; Genomic_DNA.
DR RefSeq; XP_011391764.1; XM_011393462.1.
DR AlphaFoldDB; Q4P4U7; -.
DR STRING; 5270.UM04866P0; -.
DR EnsemblFungi; KIS66807; KIS66807; UMAG_10856.
DR GeneID; 23566830; -.
DR KEGG; uma:UMAG_10856; -.
DR VEuPathDB; FungiDB:UMAG_10856; -.
DR eggNOG; KOG3880; Eukaryota.
DR HOGENOM; CLU_029663_3_1_1; -.
DR InParanoid; Q4P4U7; -.
DR OrthoDB; 1037817at2759; -.
DR Proteomes; UP000000561; Chromosome 17.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005773; C:vacuole; IBA:GO_Central.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR GO; GO:0051453; P:regulation of intracellular pH; IBA:GO_Central.
DR InterPro; IPR003492; Battenin_disease_Cln3.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR10981; PTHR10981; 1.
DR Pfam; PF02487; CLN3; 1.
DR PRINTS; PR01315; BATTENIN.
DR SUPFAM; SSF103473; SSF103473; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport; Vacuole.
FT CHAIN 1..545
FT /note="Protein BTN1"
FT /id="PRO_0000256265"
FT TRANSMEM 66..86
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 97..117
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 127..147
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 205..225
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 234..254
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 322..342
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 408..428
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 440..460
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 23..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 276..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..294
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 545 AA; 58873 MW; 8ADB2D9EC20A5EDD CRC64;
MVTIEALPLR PIEGEQQALH VGAHSSASDP RRTMVTNTSE SPLASRQATL TTSTRQKHTS
YRLNTAFFLF GLLNNSLYVV ILTAALELLP QGVPTGLVSF ANIFPALIAK AIWPYFLRGQ
VRYSKRVWSC AALSFIGMLL VSFFPALAMR LVGISLASFS SGLGELTFLQ LSTRYAPKSS
ETRSGLTAAQ AAGAGLETSF AGDAVGWFAS GTGAAGLIGA AAWWVVRPLG VQTGMAILSV
LPAFMIMAYA IILPSVQELL EGKDGKGGAM YAPLSTEDDA VERSSSDDQP TTANDDRQDS
TIHIGPGSEQ DVKVRLSFQE KMALLKPMLQ PYIIPLVIVY AMEYTINQGI APTLIYPLPT
RSSHPLLSHI IRKLTDYYPL YQLVYQTFVF LSRSSISIFK LPAIPRHLLW LPAVLQTGLL
AVLLTESLYA WFRESIASPL VIVLICVEGL AGGSAYVSVF YSIGVDEQGR GIALPSTGEE
VDDEGQEEDS AYTMAKKAQE HEFRIGCVGF GDSLGILAAS LISMPLQVSL CDAQVRSGRD
LCKQT
