TOLB_SALCH
ID TOLB_SALCH Reviewed; 430 AA.
AC Q57RK3;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 10-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 83.
DE RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE Flags: Precursor;
GN Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=SCH_0752;
OS Salmonella choleraesuis (strain SC-B67).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=321314;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC-B67;
RX PubMed=15781495; DOI=10.1093/nar/gki297;
RA Chiu C.-H., Tang P., Chu C., Hu S., Bao Q., Yu J., Chou Y.-Y., Wang H.-S.,
RA Lee Y.-S.;
RT "The genome sequence of Salmonella enterica serovar Choleraesuis, a highly
RT invasive and resistant zoonotic pathogen.";
RL Nucleic Acids Res. 33:1690-1698(2005).
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. TolB occupies a key intermediary
CC position in the Tol-Pal system because it communicates directly with
CC both membrane-embedded components, Pal in the outer membrane and TolA
CC in the inner membrane. {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
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DR EMBL; AE017220; AAX64658.1; -; Genomic_DNA.
DR RefSeq; WP_001539503.1; NC_006905.1.
DR AlphaFoldDB; Q57RK3; -.
DR SMR; Q57RK3; -.
DR EnsemblBacteria; AAX64658; AAX64658; SCH_0752.
DR KEGG; sec:SCH_0752; -.
DR HOGENOM; CLU_047123_0_0_6; -.
DR OMA; VREPSWG; -.
DR Proteomes; UP000000538; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR Gene3D; 2.120.10.30; -; 1.
DR HAMAP; MF_00671; TolB; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR014167; Tol-Pal_TolB.
DR InterPro; IPR007195; TolB_N.
DR Pfam; PF07676; PD40; 4.
DR Pfam; PF04052; TolB_N; 1.
DR TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Periplasm; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT CHAIN 22..430
FT /note="Tol-Pal system protein TolB"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT /id="PRO_0000259087"
SQ SEQUENCE 430 AA; 46179 MW; 241E5ED88306C1F4 CRC64;
MKQALRVAFG FLMLWAAVLH AEVRIEITQG VDSARPIGVV PFKWAGPGAA PEDIGGIVAA
DLRNSGKFNP LDRSRLPQQP ATAQEVQPTA WSALGIDAVV VGQVTPNPDG SYNIAYQLVD
TGGAPGTVLA QNSYKVNKQW LRYAGHTASD EVFEKLTGIK GAFRTRIAYV VQTNGGQFPY
ELRVSDYDGY NQFVVHRSPQ PLMSPAWSPD GSKLAYVTFE SGRSALVIQT LANGSVRQVA
SFPRHNGAPA FSPDGTKLAF ALSKTGSLNL YVMDLASGQI RQITDGRSNN TEPTWFPDSQ
TLAFTSDQAG RPQVYKMNIN GGAAQRITWE GSQNQDADVS SDGKFMVMVS SNNGQQHIAK
QDLVTGGVQV LSSTFLDETP SLAPNGTMVI YSSSQGMGSV LNLVSTDGRF KARLPATDGQ
VKSPAWSPYL