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TOLB_SALTY
ID   TOLB_SALTY              Reviewed;         430 AA.
AC   Q8ZQT5;
DT   11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=STM0748;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. TolB occupies a key intermediary
CC       position in the Tol-Pal system because it communicates directly with
CC       both membrane-embedded components, Pal in the outer membrane and TolA
CC       in the inner membrane. {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; AE006468; AAL19692.1; -; Genomic_DNA.
DR   RefSeq; NP_459733.1; NC_003197.2.
DR   RefSeq; WP_001562341.1; NC_003197.2.
DR   PDB; 6PNV; X-ray; 1.42 A; A=23-430.
DR   PDBsum; 6PNV; -.
DR   AlphaFoldDB; Q8ZQT5; -.
DR   SMR; Q8ZQT5; -.
DR   STRING; 99287.STM0748; -.
DR   PaxDb; Q8ZQT5; -.
DR   EnsemblBacteria; AAL19692; AAL19692; STM0748.
DR   GeneID; 1252268; -.
DR   KEGG; stm:STM0748; -.
DR   PATRIC; fig|99287.12.peg.784; -.
DR   HOGENOM; CLU_047123_0_0_6; -.
DR   OMA; VREPSWG; -.
DR   PhylomeDB; Q8ZQT5; -.
DR   BioCyc; SENT99287:STM0748-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 4.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cell cycle; Cell division; Periplasm; Reference proteome;
KW   Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           22..430
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_0000034685"
FT   STRAND          26..29
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          34..39
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          46..49
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   HELIX           54..64
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          67..70
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   HELIX           73..75
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          81..83
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   HELIX           88..92
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   TURN            93..95
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          98..106
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          112..120
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          122..124
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          128..136
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   HELIX           138..140
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   HELIX           141..157
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          166..172
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          180..186
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          193..200
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          202..207
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          211..218
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          225..230
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   TURN            231..233
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          236..240
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          246..251
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          255..262
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          269..274
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   TURN            275..277
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          280..282
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          286..288
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          290..295
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          299..306
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          313..318
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          330..339
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          343..352
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          355..362
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   TURN            363..365
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          368..370
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          374..382
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          386..394
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          399..405
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          411..414
FT                   /evidence="ECO:0007829|PDB:6PNV"
FT   STRAND          419..426
FT                   /evidence="ECO:0007829|PDB:6PNV"
SQ   SEQUENCE   430 AA;  46149 MW;  2B31AB061FFFCE27 CRC64;
     MKQALRVAFG FLMLWAAVLH AEVRIEITQG VDSARPIGVV PFKWAGPGAA PEDIGGIVAA
     DLRNSGKFNP LDRSRLPQQP ATAQEVQPTA WSALGIDAVV VGQVTPNPDG SYNVAYQLVD
     TGGAPGTVLA QNSYKVNKQW LRYAGHTASD EVFEKLTGIK GAFRTRIAYV VQTNGGQFPY
     ELRVSDYDGY NQFVVHRSPQ PLMSPAWSPD GSKLAYVTFE SGRSALVIQT LANGAVRQVA
     SFPRHNGAPA FSPDGTKLAF ALSKTGSLNL YVMDLASGQI RQITDGRSNN TEPTWFPDSQ
     TLAFTSDQAG RPQVYKMNIN GGAAQRITWE GSQNQDADVS SDGKFMVMVS SNNGQQHIAK
     QDLVTGGVQV LSSTFLDETP SLAPNGTMVI YSSSQGMGSV LNLVSTDGRF KARLPATDGQ
     VKSPAWSPYL
 
 
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