ID   TOLB_SERP5              Reviewed;         430 AA.
AC   A8GB93;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=Spro_1279;
OS   Serratia proteamaculans (strain 568).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Serratia.
OX   NCBI_TaxID=399741;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=568;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L.,
RA   Vangronsveld J., van der Lelie D., Richardson P.;
RT   "Complete sequence of chromosome of Serratia proteamaculans 568.";
RL   Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. TolB occupies a key intermediary
CC       position in the Tol-Pal system because it communicates directly with
CC       both membrane-embedded components, Pal in the outer membrane and TolA
CC       in the inner membrane. {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; CP000826; ABV40383.1; -; Genomic_DNA.
DR   RefSeq; WP_012005713.1; NC_009832.1.
DR   AlphaFoldDB; A8GB93; -.
DR   SMR; A8GB93; -.
DR   STRING; 399741.Spro_1279; -.
DR   PRIDE; A8GB93; -.
DR   EnsemblBacteria; ABV40383; ABV40383; Spro_1279.
DR   KEGG; spe:Spro_1279; -.
DR   eggNOG; COG0823; Bacteria.
DR   HOGENOM; CLU_047123_0_0_6; -.
DR   OMA; VREPSWG; -.
DR   OrthoDB; 821953at2; -.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 4.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           22..430
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_5000279151"
SQ   SEQUENCE   430 AA;  45947 MW;  BA9134A72ECE7DCE CRC64;
     MKQAFRVALG FLILWASVLH AEVRIEITQG VDSARPIGVV PFKWAGPGTP PEDIGKIVGA
     DLRNSGKFNP IDVARMPQQP TTASEVTPAA WTALGIDAVV VGQVQPGADG GYLISYQLVD
     TSGSPGTVLA QNQYKVTKQW LRYSAHTASD EVFEKLTGIK GAFRTRIAYV VQTNGGKFPY
     ELRVADYDGY NQFTVHRSPE PLMSPAWSPD GSKLAYVTFE SGRSALVVQT LANGAIRQIA
     SFPRHNGAPA FSPDGSRLAF ALSKSGSLNL YVMNLGSGQI TQITDGRSNN TEPTWFPDGQ
     SLAYTSDQGG RPQIYKVSAS GGASQRLTWE GSQNQDSEVS SDGKFLVMVS SNSGAQHIAK
     QDLGSGAVQV LTGTFLDETP SIAPNGTMVI YSSTQGMGSV LQLVSTDGRF KARLPATDGQ
     VKFPAWSPYL