ID   TOLB_SYNAS              Reviewed;         452 AA.
AC   Q2LRP7;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 2.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=SYNAS_08750;
GN   ORFNames=SYN_00188;
OS   Syntrophus aciditrophicus (strain SB).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Syntrophales; Syntrophaceae;
OC   Syntrophus.
OX   NCBI_TaxID=56780;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SB;
RX   PubMed=17442750; DOI=10.1073/pnas.0610456104;
RA   McInerney M.J., Rohlin L., Mouttaki H., Kim U., Krupp R.S.,
RA   Rios-Hernandez L., Sieber J., Struchtemeyer C.G., Bhattacharyya A.,
RA   Campbell J.W., Gunsalus R.P.;
RT   "The genome of Syntrophus aciditrophicus: life at the thermodynamic limit
RT   of microbial growth.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:7600-7605(2007).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABC76754.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000252; ABC76754.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; Q2LRP7; -.
DR   SMR; Q2LRP7; -.
DR   STRING; 56780.SYN_00188; -.
DR   PRIDE; Q2LRP7; -.
DR   EnsemblBacteria; ABC76754; ABC76754; SYN_00188.
DR   KEGG; sat:SYN_00188; -.
DR   eggNOG; COG0823; Bacteria.
DR   HOGENOM; CLU_047123_2_0_7; -.
DR   Proteomes; UP000001933; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 2.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 5.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..31
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           32..452
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_0000259094"
SQ   SEQUENCE   452 AA;  49365 MW;  07F2DFC2BE98A60A CRC64;
     MCGVRRGMGV LLLFCAVALC AMPFVVRSVW GKVYIDIDSP AFQKIPIAVA DFAPLNGNQG
     HADLSSWFPG AVRKTLDLTG YFNILNRTGG PRDQSQTGAV QAQAAYGEWR SLGAEYLIQG
     GFSSRGTQLV AEFRLIDIVQ GRQLMGKQYT GGFEDRRDMV IRFVQEVLSL LTGGEGFFDT
     RIAFVVRQGR SSSLHTVGFG SQIDGRDLAR VAGSPSLILS PRWSPDGRYL AFSSYRDGKP
     DIFVVSPSGS GLKKIVSFQG LNLPGAWSPD GRSLLLTLSK DGNEEIYVMD VRSGQVRRLT
     RNSAIDVSPV WSPDGRRIAF VSNISGSPQI YVMNADGGDV RRLTYSGNYN TTPAWSPRGG
     KIAYEGKVGS GYQIFSIDED GGNVRQLTSG AGDHEFPSWS PDGRFLTFSL RSGGRSRINI
     LNANTLEVRT LYESTDRCLG PAWSPRLKQA LR