位置:首页 > 蛋白库 > TOLB_VIBCH
TOLB_VIBCH
ID   TOLB_VIBCH              Reviewed;         450 AA.
AC   Q9KR11;
DT   11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=VC_1836;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE003852; AAF94984.1; -; Genomic_DNA.
DR   PIR; H82151; H82151.
DR   RefSeq; NP_231470.1; NC_002505.1.
DR   RefSeq; WP_000476637.1; NZ_LT906614.1.
DR   AlphaFoldDB; Q9KR11; -.
DR   SMR; Q9KR11; -.
DR   STRING; 243277.VC_1836; -.
DR   DNASU; 2613590; -.
DR   EnsemblBacteria; AAF94984; AAF94984; VC_1836.
DR   GeneID; 57740471; -.
DR   KEGG; vch:VC_1836; -.
DR   PATRIC; fig|243277.26.peg.1752; -.
DR   eggNOG; COG0823; Bacteria.
DR   HOGENOM; CLU_047123_0_0_6; -.
DR   OMA; VREPSWG; -.
DR   BioCyc; VCHO:VC1836-MON; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 3.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           23..450
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_0000034689"
SQ   SEQUENCE   450 AA;  49645 MW;  360F2A88E9663505 CRC64;
     MFKRLVFVLM LIGTGFSNIA NAALELVITD GIDSARPIAI VPFKWEGATK LPEDVSAVIA
     SDLQRSGKFS PVPTSKMPQT PYSEEQVNFG KWTSMGVDSL LTGTITQNAE GSYVISYQLV
     DIVRGQLTQG QSKALSQDGQ LVLSKDHVLF NKVATVPASR MREYAHRIAD LVYEELTGER
     GAFLTRIAYV VVNDKDPYPY QLRIADYDGY NERLVLRSKQ PLMSPAWSPD GQTLAYVSFQ
     NGQAEIYMMN IYSGKREKLT SFPRHNGAPR FSPDGKTLAL VLSKTGNLQV YTMDLATRRL
     TEVTSGRSNN TEPFWHPDGK SLIFTSDRGG KPQIYQVNLS GGETKRLTWQ GSQNLGGQIT
     PDGKFLVMVN RSDSGFNLAK QDLETGAMQI LTKTLLDESP SIAPNGGMVI YSSIYNKANV
     LSMVSIDGRF KARLPATNGR VRAPAWSPFL
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024