ID   TOLB_VIBPA              Reviewed;         450 AA.
AC   Q87QT9;
DT   11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=VP1060;
OS   Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=223926;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RIMD 2210633;
RX   PubMed=12620739; DOI=10.1016/s0140-6736(03)12659-1;
RA   Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA   Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA   Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT   "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT   distinct from that of V. cholerae.";
RL   Lancet 361:743-749(2003).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; BA000031; BAC59323.1; -; Genomic_DNA.
DR   RefSeq; NP_797439.1; NC_004603.1.
DR   RefSeq; WP_005459807.1; NC_004603.1.
DR   AlphaFoldDB; Q87QT9; -.
DR   SMR; Q87QT9; -.
DR   STRING; 223926.28806047; -.
DR   EnsemblBacteria; BAC59323; BAC59323; BAC59323.
DR   GeneID; 1188564; -.
DR   KEGG; vpa:VP1060; -.
DR   PATRIC; fig|223926.6.peg.1005; -.
DR   eggNOG; COG0823; Bacteria.
DR   HOGENOM; CLU_047123_0_0_6; -.
DR   OMA; VREPSWG; -.
DR   Proteomes; UP000002493; Chromosome 1.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 3.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           23..450
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_0000034691"
SQ   SEQUENCE   450 AA;  49786 MW;  2F760B94093F6577 CRC64;
     MIKRLLLGMF VLLGSLTNVA HAALELVITD GIDSARPIAV VPFKWEGSQP LPTDISAVIA
     SDLQRSGKFS PVPTNKMPQT PFNESEVNFD SWTSLGVDAL LTGSIKQNEQ GDYVVNYQLV
     DVVRGQLTGG QSKALGSDGE LVLSKDHVLF NKVATVKGPR MREYAHRISD LVYEQLTGER
     GAFMTRIAYV VVNDKDRFPY QLRVADYDGY NERLVLRSKQ PLMSPAWSPD GQKLAYVSFQ
     NGQAEIFIMN IYTGEREKIT SYPRHNGAPR FSPDGNKLAL VLSKTGTLQV YTFDLKTRKL
     TQITRSRSNN TEPFWHPDGK SLIFTSDRGG KPQIYQVNLG SGSIDRLTWQ GSQNLGGQIT
     PDGRFLVMVN RSDSGFNLAK QDLETGALQV LTKTLLDESP SIAPNGGMVV YSSIYNKKNV
     LSMVSIDGRF KARLPATNGR VRAPAWSPFL