TOLB_VIBVU
ID TOLB_VIBVU Reviewed; 449 AA.
AC Q8DAM3;
DT 11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT 27-JUL-2011, sequence version 2.
DT 25-MAY-2022, entry version 100.
DE RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE Flags: Precursor;
GN Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=VV1_2170;
OS Vibrio vulnificus (strain CMCP6).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=216895;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CMCP6;
RA Rhee J.H., Kim S.Y., Chung S.S., Kim J.J., Moon Y.H., Jeong H., Choy H.E.;
RT "Complete genome sequence of Vibrio vulnificus CMCP6.";
RL Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
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DR EMBL; AE016795; AAO10555.2; -; Genomic_DNA.
DR RefSeq; WP_011080047.1; NC_004459.3.
DR AlphaFoldDB; Q8DAM3; -.
DR SMR; Q8DAM3; -.
DR EnsemblBacteria; AAO10555; AAO10555; VV1_2170.
DR KEGG; vvu:VV1_2170; -.
DR HOGENOM; CLU_047123_0_0_6; -.
DR Proteomes; UP000002275; Chromosome 1.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR Gene3D; 2.120.10.30; -; 1.
DR HAMAP; MF_00671; TolB; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR014167; Tol-Pal_TolB.
DR InterPro; IPR007195; TolB_N.
DR Pfam; PF07676; PD40; 3.
DR Pfam; PF04052; TolB_N; 1.
DR TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Periplasm; Signal.
FT SIGNAL 1..22
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT CHAIN 23..449
FT /note="Tol-Pal system protein TolB"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT /id="PRO_0000034692"
SQ SEQUENCE 449 AA; 49859 MW; A84BF39BB3C4AB13 CRC64;
MKKRLLMGLL VLLSSVTNVA NAALELIITD GIDSARPIAI VPFKWQGTKA LPVDISSVVA
SDLQRSGKFS PVPTSKMPQT PYNESEINFD AWTNLGVDTL LTGSVTQNEK GEYVINYQLV
DVVRGQLTSG QSRALEDGQL VLSKDHVLFN KVATITAPRM REYAHRISDL IYEQLTGERG
AFLTRIAYVV VNDKDKFPYQ LRVADYDGFN ERLVLRSKQP LMSPAWSPDG RRLAYVSFQN
GQAEIFVLNI YTGEHEKLTS FPRHNGAPRF SPDGKKLAIV LSKTGSLQIY TLDLQTRQLT
QITRDRSNNT EPFWHPDGKS LIFTSDRGGK PQIYRVNLSD GSTSRLTWQG SQNLGGQITP
DGRFLIMVNR SDSGFNLAKQ DLETGAVQVL TKTLLDESPS IAPNGGMVIY SSIYDKKNVL
SMVSIDGRFK ARLPATNGRV RAPAWSPFL