ID   TOLB_WIGBR              Reviewed;         431 AA.
AC   Q8D2E2;
DT   11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=WIGBR4120;
OS   Wigglesworthia glossinidia brevipalpis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Wigglesworthia.
OX   NCBI_TaxID=36870;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12219091; DOI=10.1038/ng986;
RA   Akman L., Yamashita A., Watanabe H., Oshima K., Shiba T., Hattori M.,
RA   Aksoy S.;
RT   "Genome sequence of the endocellular obligate symbiont of tsetse flies,
RT   Wigglesworthia glossinidia.";
RL   Nat. Genet. 32:402-407(2002).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. TolB occupies a key intermediary
CC       position in the Tol-Pal system because it communicates directly with
CC       both membrane-embedded components, Pal in the outer membrane and TolA
CC       in the inner membrane. {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; BA000021; BAC24558.1; -; Genomic_DNA.
DR   RefSeq; WP_011070216.1; NC_004344.2.
DR   AlphaFoldDB; Q8D2E2; -.
DR   SMR; Q8D2E2; -.
DR   STRING; 36870.25166368; -.
DR   EnsemblBacteria; BAC24558; BAC24558; BAC24558.
DR   KEGG; wbr:tolB; -.
DR   eggNOG; COG0823; Bacteria.
DR   HOGENOM; CLU_047123_0_0_6; -.
DR   OMA; VREPSWG; -.
DR   OrthoDB; 821953at2; -.
DR   Proteomes; UP000000562; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 4.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           20..431
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_0000034694"
SQ   SEQUENCE   431 AA;  48625 MW;  866310B238B8EE88 CRC64;
     MKRLLFFLIC VFFSKTSYSN VDISINKGID ISTPIGISSF EWVEVNENNN YENISKIISC
     DLQNSGKFSP IEIYKESNKS IEKQIKNNSI NLNKLNINTI LTGKISLNYN GEYLISYKLI
     DLVNYPGKIL LSGYRTVHLQ SFRKVAHEIS NEIFKKLTGI QGVFHTRIAY ILYNKNNEYK
     YKLCISDYDG YNQNIIHQSN MPLMSPSWSP DGKKIAYVTF EKGSSEIKIK DIKTGSIKHI
     SSFPYHNGAP AFSPNGENLA FALSKTGSLN LYVMNLKNGY IKQITHGNSN NTEPSWFPDN
     NSLAYTSDQS GTPQIYKINI SNGKFNRLSW LGSKNQNANV SPDGKFIAMV NSEKKSQHIA
     LFDINMDNAK IITETFLDEA PSISPNNVMI IYTSSYGDSS VIELISTNGR FKTSILKING
     QIKFPAWSQK I