ID   TOLB_WOLPM              Reviewed;         420 AA.
AC   Q73IV6;
DT   07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=WD_0038;
OS   Wolbachia pipientis wMel.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Anaplasmataceae; Wolbachieae; Wolbachia; unclassified Wolbachia.
OX   NCBI_TaxID=163164;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15024419; DOI=10.1371/journal.pbio.0020069;
RA   Wu M., Sun L.V., Vamathevan J.J., Riegler M., DeBoy R.T., Brownlie J.C.,
RA   McGraw E.A., Martin W., Esser C., Ahmadinejad N., Wiegand C., Madupu R.,
RA   Beanan M.J., Brinkac L.M., Daugherty S.C., Durkin A.S., Kolonay J.F.,
RA   Nelson W.C., Mohamoud Y., Lee P., Berry K.J., Young M.B., Utterback T.R.,
RA   Weidman J.F., Nierman W.C., Paulsen I.T., Nelson K.E., Tettelin H.,
RA   O'Neill S.L., Eisen J.A.;
RT   "Phylogenomics of the reproductive parasite Wolbachia pipientis wMel: a
RT   streamlined genome overrun by mobile genetic elements.";
RL   PLoS Biol. 2:327-341(2004).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; AE017196; AAS13804.1; -; Genomic_DNA.
DR   RefSeq; WP_010962324.1; NC_002978.6.
DR   AlphaFoldDB; Q73IV6; -.
DR   SMR; Q73IV6; -.
DR   STRING; 163164.WD_0038; -.
DR   EnsemblBacteria; AAS13804; AAS13804; WD_0038.
DR   GeneID; 29555260; -.
DR   KEGG; wol:WD_0038; -.
DR   eggNOG; COG0823; Bacteria.
DR   OMA; WLPNGRE; -.
DR   OrthoDB; 821953at2; -.
DR   Proteomes; UP000008215; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 5.
DR   Pfam; PF04052; TolB_N; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           22..420
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_0000034695"
SQ   SEQUENCE   420 AA;  46549 MW;  8494C18911474151 CRC64;
     MKLFVHLVLF ISLFIPYFTK AALYVDIKKS SVGNIGLVVS KCTCKTALES ELSENIAKVI
     GTNLSNCGLF NVKRSAEAES KSWKSDTVVT VSLSEISGSA LELSFRLFDA FTKRELLTQS
     VVFPAKDWRK IGHLVSDVIH DRLIGEKGHF NTKITYIAEE KDSNYKSVRK IAVMNQDGSN
     IKYLTNGDRF VSTPRFSPNG KGIVYISYAN GKSYIILKNL KDNTESIISA FEGVVSAPRF
     SPDGKSLLIS HSLGGETNIL SLDLSSKRTK KITKGSAIST SPSFSPDQKY MAFSSDISGS
     QQLYVIDFTN KSKKPKRISF GSGRYATPVW SPKGDLIAFT KIQSGKFYIG VMKPDGKEER
     LLSEGHKIES PAWLPNGREI IFTRTESPSN SKLYLVDLVK KNQKMVSTPT NASLPDWSYF