ID   TOLB_WOLPP              Reviewed;         418 AA.
AC   B3CP06;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   22-JUL-2008, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=WP0225;
OS   Wolbachia pipientis subsp. Culex pipiens (strain wPip).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Anaplasmataceae; Wolbachieae; Wolbachia; unclassified Wolbachia.
OX   NCBI_TaxID=570417;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=wPip;
RX   PubMed=18550617; DOI=10.1093/molbev/msn133;
RA   Klasson L., Walker T., Sebaihia M., Sanders M.J., Quail M.A., Lord A.,
RA   Sanders S., Earl J., O'Neill S.L., Thomson N., Sinkins S.P., Parkhill J.;
RT   "Genome evolution of Wolbachia strain wPip from the Culex pipiens group.";
RL   Mol. Biol. Evol. 25:1877-1887(2008).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; AM999887; CAQ54333.1; -; Genomic_DNA.
DR   RefSeq; WP_012481764.1; NC_010981.1.
DR   AlphaFoldDB; B3CP06; -.
DR   SMR; B3CP06; -.
DR   STRING; 570417.WP0225; -.
DR   EnsemblBacteria; CAQ54333; CAQ54333; WP0225.
DR   KEGG; wpi:WP0225; -.
DR   eggNOG; COG0823; Bacteria.
DR   HOGENOM; CLU_047123_0_0_5; -.
DR   OMA; WLPNGRE; -.
DR   OrthoDB; 821953at2; -.
DR   Proteomes; UP000008814; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 4.
DR   Pfam; PF04052; TolB_N; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           22..418
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_1000131539"
SQ   SEQUENCE   418 AA;  46866 MW;  7FBABE8B2A509DE3 CRC64;
     MKLFVQLVLF ISLFIPYSTK AVLYVDIKKS NIGNIDLVVS KCACKTEVEN ELSESITKVI
     ETNLSNCGLF NVKRDAKVES WKSDTVVTIS LSEVSNRNLE LSFRLSDSFT NRELLTQSVV
     FLAKDWRKIS HLVSDLIHDR LIGEKGHFNT KITYIAEEKD SNYKSVRKIA VMNQDGSNIK
     YLTNGEKFVS TPRFSPNGKG IVYISYTNGK SYIILKNLKD NTESIISAFE GVISAPRFSP
     DGKSLFISHS LSGETNILSL DLSSKRTKKI TKGSAISTSP SLSPDQKYMV FSSDISGSQQ
     LYIIDFTKKS KKPKRISFGN GRYATPVWSP KGDLIAFTKI QSGKFYIGVM KPDGKEERLL
     SEGHKIESPA WLPNGREIIF TNAESPSNSK LYLVDLVKKN QKMVFTPTNA SLPDWSYF