TOLB_WOLWR
ID TOLB_WOLWR Reviewed; 420 AA.
AC C0R560;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-MAY-2009, sequence version 1.
DT 25-MAY-2022, entry version 69.
DE RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE Flags: Precursor;
GN Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=WRi_000320;
OS Wolbachia sp. subsp. Drosophila simulans (strain wRi).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC Anaplasmataceae; Wolbachieae; Wolbachia; unclassified Wolbachia.
OX NCBI_TaxID=66084;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=wRi;
RX PubMed=19307581; DOI=10.1073/pnas.0810753106;
RA Klasson L., Westberg J., Sapountzis P., Naeslund K., Lutnaes Y.,
RA Darby A.C., Veneti Z., Chen L., Braig H.R., Garrett R., Bourtzis K.,
RA Andersson S.G.;
RT "The mosaic genome structure of the Wolbachia wRi strain infecting
RT Drosophila simulans.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:5725-5730(2009).
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
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DR EMBL; CP001391; ACN94902.1; -; Genomic_DNA.
DR RefSeq; WP_007548937.1; NZ_MKIF01000138.1.
DR AlphaFoldDB; C0R560; -.
DR SMR; C0R560; -.
DR STRING; 66084.WRi_000320; -.
DR EnsemblBacteria; ACN94902; ACN94902; WRi_000320.
DR KEGG; wri:WRi_000320; -.
DR HOGENOM; CLU_047123_0_0_5; -.
DR OMA; WLPNGRE; -.
DR Proteomes; UP000001293; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR Gene3D; 2.120.10.30; -; 1.
DR HAMAP; MF_00671; TolB; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR014167; Tol-Pal_TolB.
DR InterPro; IPR007195; TolB_N.
DR Pfam; PF07676; PD40; 5.
DR Pfam; PF04052; TolB_N; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Periplasm; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT CHAIN 22..420
FT /note="Tol-Pal system protein TolB"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT /id="PRO_1000147666"
SQ SEQUENCE 420 AA; 46579 MW; B3B11CDDC54A1344 CRC64;
MKLFVHLVLF ISLFIPYFTK AALYVDIKKS SVGNIGLVVS KCTCKTALES ELSENIAKVI
GTNLSNCGLF NVKRGAEAES KSWKSDTVVT VSLSEISGSA LELSFRLFDT FTKRELLTQS
VVFPAKDWRK IGHLVSDVIH DRLIGEKGHF NTKITYIAEE KDSNYKSVRK IAVMNQDGSN
IKYLTNGDRF VSTPRFSPNG KGIVYISYAN GKSYIILKNL KDNTESIIST FEGVVSAPRF
SPDGKSLLIS HSLGGETNIL SLDLSSKRTK KITKGSAIST SPSFSPDQKY MAFSSDISGS
QQLYVIDFTN KSKKPKRISF GSGRYATPVW SPKGDLIAFT KIQSGKFYIG VMKPDGKEER
LLSEGHKIES PAWLPNGREI IFTRTESPSN SKLYLVDLVK KNQKMVSTPT NASLPDWSYF