ID   TOLB_YERPA              Reviewed;         430 AA.
AC   Q1CAF2;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=YPA_0602;
OS   Yersinia pestis bv. Antiqua (strain Antiqua).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=360102;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Antiqua;
RX   PubMed=16740952; DOI=10.1128/jb.00124-06;
RA   Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M.,
RA   Worsham P., Chu M.C., Andersen G.L.;
RT   "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516:
RT   evidence of gene reduction in an emerging pathogen.";
RL   J. Bacteriol. 188:4453-4463(2006).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. TolB occupies a key intermediary
CC       position in the Tol-Pal system because it communicates directly with
CC       both membrane-embedded components, Pal in the outer membrane and TolA
CC       in the inner membrane. {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; CP000308; ABG12570.1; -; Genomic_DNA.
DR   RefSeq; WP_002210738.1; NZ_CP009906.1.
DR   AlphaFoldDB; Q1CAF2; -.
DR   SMR; Q1CAF2; -.
DR   EnsemblBacteria; ABG12570; ABG12570; YPA_0602.
DR   GeneID; 66842411; -.
DR   KEGG; ypa:YPA_0602; -.
DR   OMA; VREPSWG; -.
DR   Proteomes; UP000001971; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 4.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           22..430
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_0000259100"
SQ   SEQUENCE   430 AA;  46045 MW;  3A64DDE78A56529B CRC64;
     MKQAFRVALG FLVLWASVLH AEVRIEITQG VDSARPIGVV PFKWMGPGTP PEEIGAIVGA
     DLRNSGKFNP IDAARMPQQP STAAEVTPAA WTALGIDAVV VGQVQPSADG SYVVSYQLVD
     TSGSAGSILA QNQYKVTKQW LRYSAHTVSD EVFEKLTGIK GAFRTRIAYV VKTNGGKFPH
     ELRVSDYDGY NQFVVHRSPE PLMSPAWSPD GSKIAYVTFE SGKSALVIQT LANGAIRQVA
     SFPRHNGAPA FSPDGTKLAF ALSKSGSLNL YVMDLASGQI SQVTDGRSNN TEPSWFPDSQ
     NLAYTSDQGG RPQVYKVNIN GGVPQRITWE GSQNQNADVS PDGKFLVLVS SNGGAQHIAK
     QDLETGAVQV LTDTLLDETP SIAPNGTMVI YSSTQGLGSV LQLVSTDGRF KARLPATDGQ
     VKFPAWSPYL