TOLQ_PSEAE
ID TOLQ_PSEAE Reviewed; 231 AA.
AC P50598;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Tol-Pal system protein TolQ {ECO:0000255|HAMAP-Rule:MF_02202};
GN Name=tolQ {ECO:0000255|HAMAP-Rule:MF_02202}; OrderedLocusNames=PA0969;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=PAO;
RX PubMed=8955385; DOI=10.1128/jb.178.24.7059-7068.1996;
RA Dennis J.J., Lafontaine E.R., Sokol P.A.;
RT "Identification and characterization of the tolQRA genes of Pseudomonas
RT aeruginosa.";
RL J. Bacteriol. 178:7059-7068(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC Rule:MF_02202}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000255|HAMAP-Rule:MF_02202}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_02202, ECO:0000305}; Multi-pass membrane protein
CC {ECO:0000255|HAMAP-Rule:MF_02202, ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ExbB/TolQ family. {ECO:0000255|HAMAP-
CC Rule:MF_02202, ECO:0000305}.
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DR EMBL; U39558; AAC44658.1; -; Genomic_DNA.
DR EMBL; AE004091; AAG04358.1; -; Genomic_DNA.
DR PIR; C83525; C83525.
DR RefSeq; NP_249660.1; NC_002516.2.
DR RefSeq; WP_003086125.1; NZ_QZGE01000007.1.
DR AlphaFoldDB; P50598; -.
DR SMR; P50598; -.
DR STRING; 287.DR97_968; -.
DR PaxDb; P50598; -.
DR PRIDE; P50598; -.
DR DNASU; 882055; -.
DR EnsemblBacteria; AAG04358; AAG04358; PA0969.
DR GeneID; 882055; -.
DR KEGG; pae:PA0969; -.
DR PATRIC; fig|208964.12.peg.1007; -.
DR PseudoCAP; PA0969; -.
DR HOGENOM; CLU_053325_2_2_6; -.
DR InParanoid; P50598; -.
DR OMA; SWTYIFR; -.
DR PhylomeDB; P50598; -.
DR BioCyc; PAER208964:G1FZ6-990-MON; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0043213; P:bacteriocin transport; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IBA:GO_Central.
DR HAMAP; MF_02202; TolQ; 1.
DR InterPro; IPR002898; MotA_ExbB_proton_chnl.
DR InterPro; IPR014163; Tol-Pal_TolQ.
DR Pfam; PF01618; MotA_ExbB; 1.
DR TIGRFAMs; TIGR02796; tolQ; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Cell inner membrane; Cell membrane; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..231
FT /note="Tol-Pal system protein TolQ"
FT /id="PRO_0000145825"
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02202"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02202"
FT TRANSMEM 176..196
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02202"
SQ SEQUENCE 231 AA; 25282 MW; 62E22A7E3E83C09D CRC64;
MEPNVVDHTS MWSLISNASI VVQLVMLTLV AASVTSWIMI FQRGNAMRAA KKALDAFEER
FWSGIDLSKL YRQAGSNPDP DSGVEQIFRA GFKEFSRLRQ QPGVDPDAVM EGVARAMRVA
ISREEEKLEA SLPFLATVGS TSPYVGLFGT VWGIMNSFRG LATVQQATLA TVAPGIAEAL
IATAIGLFAA IPAVIAYNRF SARSEMLIGR YYTFADEFQA ILHRKVHTSD D
