ID   TOM20_CAEBR             Reviewed;         188 AA.
AC   A8Y3V5;
DT   16-NOV-2011, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Mitochondrial import receptor subunit TOM20 homolog {ECO:0000250|UniProtKB:Q19766};
DE   AltName: Full=Translocase of outer mitochondrial membrane protein 20 {ECO:0000250|UniProtKB:Q19766};
GN   Name=tomm-20; ORFNames=CBG23457;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1] {ECO:0000312|EMBL:CAP39574.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Central component of the receptor complex responsible for the
CC       recognition and translocation of cytosolically synthesized
CC       mitochondrial preproteins. Together with TOM22 functions as the transit
CC       peptide receptor at the surface of the mitochondrion outer membrane and
CC       facilitates the movement of preproteins into the translocation pore (By
CC       similarity). {ECO:0000250|UniProtKB:P35848}.
CC   -!- SUBUNIT: Forms part of the preprotein translocase complex of the outer
CC       mitochondrial membrane (TOM complex). {ECO:0000250|UniProtKB:P35848}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000305};
CC       Single-pass membrane protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the Tom20 family. {ECO:0000255}.
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DR   EMBL; HE601533; CAP39574.1; -; Genomic_DNA.
DR   RefSeq; XP_002636734.1; XM_002636688.1.
DR   AlphaFoldDB; A8Y3V5; -.
DR   SMR; A8Y3V5; -.
DR   STRING; 6238.CBG23457; -.
DR   EnsemblMetazoa; CBG23457.1; CBG23457.1; WBGene00041813.
DR   GeneID; 8578730; -.
DR   KEGG; cbr:CBG_23457; -.
DR   CTD; 8578730; -.
DR   WormBase; CBG23457; CBP05557; WBGene00041813; Cbr-tomm-20.
DR   eggNOG; KOG4056; Eukaryota.
DR   HOGENOM; CLU_100000_1_1_1; -.
DR   InParanoid; A8Y3V5; -.
DR   OMA; HKRINAP; -.
DR   OrthoDB; 1316067at2759; -.
DR   Proteomes; UP000008549; Chromosome V.
DR   GO; GO:0031307; C:integral component of mitochondrial outer membrane; IBA:GO_Central.
DR   GO; GO:0005742; C:mitochondrial outer membrane translocase complex; IBA:GO_Central.
DR   GO; GO:0030943; F:mitochondrion targeting sequence binding; IBA:GO_Central.
DR   GO; GO:0030150; P:protein import into mitochondrial matrix; IBA:GO_Central.
DR   GO; GO:0016031; P:tRNA import into mitochondrion; IBA:GO_Central.
DR   Gene3D; 1.20.960.10; -; 1.
DR   InterPro; IPR002056; MAS20.
DR   InterPro; IPR022422; MAS20_rcpt_metazoan.
DR   InterPro; IPR023392; Tom20_dom_sf.
DR   PANTHER; PTHR12430; PTHR12430; 1.
DR   Pfam; PF02064; MAS20; 1.
DR   PRINTS; PR01989; EUOM20RECPTR.
DR   PRINTS; PR00351; OM20RECEPTOR.
DR   SUPFAM; SSF47157; SSF47157; 1.
DR   TIGRFAMs; TIGR00985; 3a0801s04tom; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion outer membrane; Protein transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..188
FT                   /note="Mitochondrial import receptor subunit TOM20 homolog"
FT                   /id="PRO_0000413850"
FT   TOPO_DOM        1..12
FT                   /note="Mitochondrial intermembrane"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        13..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        32..188
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          48..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          155..188
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   188 AA;  20560 MW;  FDA40C6C17FBC4E9 CRC64;
     MTDTLFGFNK SNVVLAAGVA GAAFLGYCIY FDHKRINAPD YKDKIRQKRR AQAGSGGMAA
     RRPPAGGNEM APDVTDPSQM QRFFLQEVQL GEELMAAGNV EEGAVHIANA VMLCGESQQL
     LSIFQQTLSE EQFRAVVQQL PSTRERLADM FGARADEAEN EPPLVQYLGD GPPPAQIQEL
     IDDTDDLE