ID   TOM20_XENTR             Reviewed;         147 AA.
AC   Q6DFM9;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Mitochondrial import receptor subunit TOM20 homolog;
DE   AltName: Full=Mitochondrial 20 kDa outer membrane protein;
DE   AltName: Full=Outer mitochondrial membrane receptor Tom20;
GN   Name=tomm20; ORFNames=TNeu065b24.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Neurula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Central component of the receptor complex responsible for the
CC       recognition and translocation of cytosolically synthesized
CC       mitochondrial preproteins. Together with tom22 functions as the transit
CC       peptide receptor at the surface of the mitochondrion outer membrane and
CC       facilitates the movement of preproteins into the tom40 translocation
CC       pore (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Forms part of the preprotein translocase complex of the outer
CC       mitochondrial membrane (TOM complex). Interacts with tom22 (By
CC       similarity). {ECO:0000250|UniProtKB:Q15388}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane
CC       {ECO:0000250|UniProtKB:Q15388}; Single-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the Tom20 family. {ECO:0000305}.
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DR   EMBL; CR760251; CAJ83083.1; -; mRNA.
DR   EMBL; BC076705; AAH76705.1; -; mRNA.
DR   RefSeq; NP_001005024.1; NM_001005024.1.
DR   AlphaFoldDB; Q6DFM9; -.
DR   SMR; Q6DFM9; -.
DR   STRING; 8364.ENSXETP00000053107; -.
DR   DNASU; 448537; -.
DR   GeneID; 448537; -.
DR   KEGG; xtr:448537; -.
DR   CTD; 9804; -.
DR   Xenbase; XB-GENE-972815; tomm20.
DR   eggNOG; KOG4056; Eukaryota.
DR   InParanoid; Q6DFM9; -.
DR   OrthoDB; 1316067at2759; -.
DR   Reactome; R-XTR-5689880; Ub-specific processing proteases.
DR   Proteomes; UP000008143; Chromosome 5.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000024650; Expressed in heart and 13 other tissues.
DR   ExpressionAtlas; Q6DFM9; baseline.
DR   GO; GO:0031307; C:integral component of mitochondrial outer membrane; IBA:GO_Central.
DR   GO; GO:0005742; C:mitochondrial outer membrane translocase complex; IBA:GO_Central.
DR   GO; GO:0030943; F:mitochondrion targeting sequence binding; IBA:GO_Central.
DR   GO; GO:0030150; P:protein import into mitochondrial matrix; IBA:GO_Central.
DR   GO; GO:0016031; P:tRNA import into mitochondrion; IBA:GO_Central.
DR   Gene3D; 1.20.960.10; -; 1.
DR   InterPro; IPR002056; MAS20.
DR   InterPro; IPR022422; MAS20_rcpt_metazoan.
DR   InterPro; IPR023392; Tom20_dom_sf.
DR   PANTHER; PTHR12430; PTHR12430; 1.
DR   Pfam; PF02064; MAS20; 1.
DR   PIRSF; PIRSF037707; MAS20_rcpt; 1.
DR   PRINTS; PR01989; EUOM20RECPTR.
DR   PRINTS; PR00351; OM20RECEPTOR.
DR   SUPFAM; SSF47157; SSF47157; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Mitochondrion outer membrane; Phosphoprotein;
KW   Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..147
FT                   /note="Mitochondrial import receptor subunit TOM20 homolog"
FT                   /id="PRO_0000317746"
FT   TOPO_DOM        1..3
FT                   /note="Mitochondrial intermembrane"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        4..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        27..147
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   147 AA;  16521 MW;  E95273EBC99344FC CRC64;
     MVVVGKTSAI AAGVCGALFL GYCIYFDRKR RSDPNFKNRL REKRRKQKIA KERAGQSRLP
     DLKDAEAVQK FFLEEIQLGE ELLAQGDFEK GVDHLTNAIA ICGQPQQLLQ VLQQTLPPPV
     FQMLLTKLPT INQRIGNAQN LAEDDVE