ID   TOM5_SCHPO              Reviewed;          49 AA.
AC   G2TRP7;
DT   18-APR-2012, integrated into UniProtKB/Swiss-Prot.
DT   16-NOV-2011, sequence version 1.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=Mitochondrial import receptor subunit tom5;
GN   Name=tom5; ORFNames=SPBC19G7.19;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=21511999; DOI=10.1126/science.1203357;
RA   Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA   Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA   Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA   Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA   French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA   Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA   Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA   Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA   Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA   Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT   "Comparative functional genomics of the fission yeasts.";
RL   Science 332:930-936(2011).
CC   -!- FUNCTION: Component of the TOM (translocase of outer membrane) receptor
CC       complex responsible for the recognition and translocation of
CC       cytosolically synthesized mitochondrial preproteins. {ECO:0000250}.
CC   -!- SUBUNIT: Forms part of the TOM (translocase of outer membrane) complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000305};
CC       Single-pass membrane protein {ECO:0000305}. Note=Outer membrane-
CC       anchored. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the Tom5 family. {ECO:0000305}.
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DR   EMBL; CU329671; CCD31371.1; -; Genomic_DNA.
DR   RefSeq; XP_004001718.1; XM_004001669.1.
DR   AlphaFoldDB; G2TRP7; -.
DR   SMR; G2TRP7; -.
DR   BioGRID; 4254113; 1.
DR   STRING; 4896.SPBC19G7.19.1; -.
DR   MaxQB; G2TRP7; -.
DR   PaxDb; G2TRP7; -.
DR   EnsemblFungi; SPBC19G7.19.1; SPBC19G7.19.1:pep; SPBC19G7.19.
DR   PomBase; SPBC19G7.19; tom5.
DR   VEuPathDB; FungiDB:SPBC19G7.19; -.
DR   HOGENOM; CLU_3143868_0_0_1; -.
DR   PRO; PR:G2TRP7; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0031307; C:integral component of mitochondrial outer membrane; IBA:GO_Central.
DR   GO; GO:0005742; C:mitochondrial outer membrane translocase complex; ISO:PomBase.
DR   GO; GO:0030150; P:protein import into mitochondrial matrix; ISO:PomBase.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; IBA:GO_Central.
DR   InterPro; IPR019603; Tom5.
DR   Pfam; PF10642; Tom5; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion outer membrane; Protein transport;
KW   Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..49
FT                   /note="Mitochondrial import receptor subunit tom5"
FT                   /id="PRO_0000416679"
FT   TOPO_DOM        1..26
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        27..44
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   49 AA;  5362 MW;  B16CAA27C9916959 CRC64;
     MFSGAGRPSK EQIKQYDNLA VGEMKKGASV AAVLLLTPFV ISFFQKMRA