ID   TOM71_ARATH             Reviewed;          75 AA.
AC   Q9ASY8;
DT   06-DEC-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=Mitochondrial import receptor subunit TOM7-1;
DE   AltName: Full=Translocase of outer membrane 7 kDa subunit 1;
GN   Name=TOM7-1; OrderedLocusNames=At5g41685; ORFNames=MBK23.22.1;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000312|EMBL:AAK32761.1};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9330910; DOI=10.1093/dnares/4.3.215;
RA   Sato S., Kotani H., Nakamura Y., Kaneko T., Asamizu E., Fukami M.,
RA   Miyajima N., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence
RT   features of the 1.6 Mb regions covered by twenty physically assigned P1
RT   clones.";
RL   DNA Res. 4:215-230(1997).
RN   [2] {ECO:0000305}
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4] {ECO:0000305}
RP   PROTEIN SEQUENCE OF 9-22 AND 26-33, AND SUBCELLULAR LOCATION.
RX   PubMed=11161051; DOI=10.1104/pp.125.2.943;
RA   Werhahn W., Niemeyer A., Jaensch L., Kruft V., Schmitz U.K., Braun H.-P.;
RT   "Purification and characterization of the preprotein translocase of the
RT   outer mitochondrial membrane from Arabidopsis. Identification of multiple
RT   forms of TOM20.";
RL   Plant Physiol. 125:943-954(2001).
RN   [5]
RP   SUBUNIT.
RA   Werhahn W., Jaensch L., Braun H.-P.;
RT   "Identification of novel subunits of the TOM complex from Arabidopsis
RT   thaliana.";
RL   Plant Physiol. Biochem. 41:407-416(2003).
RN   [6]
RP   TISSUE SPECIFICITY.
RX   PubMed=14730085; DOI=10.1104/pp.103.033910;
RA   Lister R., Chew O., Lee M.N., Heazlewood J.L., Clifton R., Parker K.L.,
RA   Millar A.H., Whelan J.;
RT   "A transcriptomic and proteomic characterization of the Arabidopsis
RT   mitochondrial protein import apparatus and its response to mitochondrial
RT   dysfunction.";
RL   Plant Physiol. 134:777-789(2004).
RN   [7]
RP   ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, AND IDENTIFICATION BY MASS
RP   SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22223895; DOI=10.1074/mcp.m111.015131;
RA   Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T.,
RA   Giglione C.;
RT   "Comparative large-scale characterisation of plant vs. mammal proteins
RT   reveals similar and idiosyncratic N-alpha acetylation features.";
RL   Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
CC   -!- FUNCTION: Seems to act as a modulator of the dynamics of the
CC       mitochondrial protein transport machinery. Seems to promote the
CC       dissociation of subunits of the outer membrane translocase (By
CC       similarity). {ECO:0000250|UniProtKB:P53507}.
CC   -!- SUBUNIT: Forms part of the preprotein translocase complex of the outer
CC       mitochondrial membrane (TOM complex) which consists of at least 6
CC       different proteins (TOM5, TOM6, TOM7, TOM20, TOM22/TOM9 and TOM40).
CC       {ECO:0000269|Ref.5}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane
CC       {ECO:0000269|PubMed:11161051}; Single-pass membrane protein
CC       {ECO:0000269|PubMed:11161051}.
CC   -!- TISSUE SPECIFICITY: Expressed in roots, flowers, young cotyledons and
CC       leaves. {ECO:0000269|PubMed:14730085}.
CC   -!- SIMILARITY: Belongs to the Tom7 family. {ECO:0000305}.
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DR   EMBL; AB005233; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002688; AED94709.1; -; Genomic_DNA.
DR   EMBL; AF361593; AAK32761.1; -; mRNA.
DR   EMBL; AY058224; AAL15398.1; -; mRNA.
DR   RefSeq; NP_568593.1; NM_123533.3.
DR   AlphaFoldDB; Q9ASY8; -.
DR   SMR; Q9ASY8; -.
DR   STRING; 3702.AT5G41685.1; -.
DR   iPTMnet; Q9ASY8; -.
DR   PaxDb; Q9ASY8; -.
DR   PRIDE; Q9ASY8; -.
DR   ProteomicsDB; 234458; -.
DR   EnsemblPlants; AT5G41685.1; AT5G41685.1; AT5G41685.
DR   GeneID; 834171; -.
DR   Gramene; AT5G41685.1; AT5G41685.1; AT5G41685.
DR   KEGG; ath:AT5G41685; -.
DR   Araport; AT5G41685; -.
DR   TAIR; locus:505006668; AT5G41685.
DR   HOGENOM; CLU_173610_0_1_1; -.
DR   InParanoid; Q9ASY8; -.
DR   OMA; PEERSAC; -.
DR   OrthoDB; 1608790at2759; -.
DR   PhylomeDB; Q9ASY8; -.
DR   PRO; PR:Q9ASY8; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9ASY8; baseline and differential.
DR   Genevisible; Q9ASY8; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005742; C:mitochondrial outer membrane translocase complex; IEA:InterPro.
DR   GO; GO:0030150; P:protein import into mitochondrial matrix; IEA:InterPro.
DR   InterPro; IPR012621; Tom7.
DR   Pfam; PF08038; Tom7; 1.
PE   1: Evidence at protein level;
KW   Acetylation; Direct protein sequencing; Membrane; Mitochondrion;
KW   Mitochondrion outer membrane; Protein transport; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..75
FT                   /note="Mitochondrial import receptor subunit TOM7-1"
FT                   /id="PRO_0000046762"
FT   TOPO_DOM        1..46
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        47..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        65..75
FT                   /note="Mitochondrial intermembrane"
FT                   /evidence="ECO:0000250"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0007744|PubMed:22223895"
SQ   SEQUENCE   75 AA;  8265 MW;  6D0E8F5980963F07 CRC64;
     MESTISLKVN KGKGKGSKGA SSSDDKSKFD VVKEWTNWSL KKAKVVTHYG FIPLVIFVGM
     NSDPKPHLFQ LLSPV