TOM7_CAEEL
ID TOM7_CAEEL Reviewed; 58 AA.
AC P34660;
DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1994, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Mitochondrial import receptor subunit TOM7 homolog;
DE AltName: Full=Translocase of outer membrane 7 kDa subunit homolog;
GN Name=tomm-7; ORFNames=ZK652.2;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=7906398; DOI=10.1038/368032a0;
RA Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA Wilkinson-Sproat J., Wohldman P.;
RT "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT elegans.";
RL Nature 368:32-38(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBUNIT: Forms part of the preprotein translocase complex of the outer
CC mitochondrial membrane (TOM complex). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250};
CC Single-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the Tom7 family. {ECO:0000305}.
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DR EMBL; FO080278; CCD62547.1; -; Genomic_DNA.
DR PIR; S44902; S44902.
DR RefSeq; NP_498706.1; NM_066305.5.
DR AlphaFoldDB; P34660; -.
DR SMR; P34660; -.
DR BioGRID; 41309; 1.
DR IntAct; P34660; 1.
DR STRING; 6239.ZK652.2; -.
DR PaxDb; P34660; -.
DR PeptideAtlas; P34660; -.
DR EnsemblMetazoa; ZK652.2.1; ZK652.2.1; WBGene00022783.
DR GeneID; 176101; -.
DR KEGG; cel:CELE_ZK652.2; -.
DR UCSC; ZK652.2; c. elegans.
DR CTD; 176101; -.
DR WormBase; ZK652.2; CE00448; WBGene00022783; tomm-7.
DR eggNOG; KOG4449; Eukaryota.
DR HOGENOM; CLU_173610_2_0_1; -.
DR InParanoid; P34660; -.
DR OMA; FRIFVQW; -.
DR OrthoDB; 1608790at2759; -.
DR PhylomeDB; P34660; -.
DR PRO; PR:P34660; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00022783; Expressed in adult organism and 3 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005742; C:mitochondrial outer membrane translocase complex; IBA:GO_Central.
DR GO; GO:0007005; P:mitochondrion organization; IMP:WormBase.
DR GO; GO:1903955; P:positive regulation of protein targeting to mitochondrion; IBA:GO_Central.
DR GO; GO:0030150; P:protein import into mitochondrial matrix; IEA:InterPro.
DR InterPro; IPR012621; Tom7.
DR Pfam; PF08038; Tom7; 1.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Mitochondrion outer membrane; Protein transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..58
FT /note="Mitochondrial import receptor subunit TOM7 homolog"
FT /id="PRO_0000046761"
FT TOPO_DOM 1..16
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 17..35
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 36..58
FT /note="Mitochondrial intermembrane"
FT /evidence="ECO:0000250"
SQ SEQUENCE 58 AA; 6318 MW; CCDFB53E51E816A9 CRC64;
MKLSPATKSF IGKTVDISTF AIQWGFVPFV VYLGFKKGAE PMPNGQILPL SAMSLLWG