TOM7_SCHPO
ID TOM7_SCHPO Reviewed; 52 AA.
AC O42999;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2016, sequence version 2.
DT 25-MAY-2022, entry version 116.
DE RecName: Full=Mitochondrial import receptor subunit tom7;
DE AltName: Full=Translocase of outer membrane 7 kDa subunit;
GN Name=tom7; ORFNames=SPBC27B12.10c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP GENE MODEL REVISION.
RX PubMed=24929437; DOI=10.1038/nsmb.2843;
RA Duncan C.D., Mata J.;
RT "The translational landscape of fission-yeast meiosis and sporulation.";
RL Nat. Struct. Mol. Biol. 21:641-647(2014).
CC -!- SUBUNIT: Forms part of the preprotein translocase complex of the outer
CC mitochondrial membrane (TOM complex) which consists of at least 8
CC different proteins (tom5, tom6, tom7, tom20, tom22, tom37, tom40 and
CC tom70).
CC -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250};
CC Single-pass membrane protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the Tom7 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA16905.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; CU329671; CAA16905.1; ALT_SEQ; Genomic_DNA.
DR PIR; T40034; T40034.
DR RefSeq; NP_595542.1; NM_001021453.2.
DR AlphaFoldDB; O42999; -.
DR SMR; O42999; -.
DR BioGRID; 277030; 2.
DR STRING; 4896.SPBC27B12.10c.1; -.
DR PaxDb; O42999; -.
DR PRIDE; O42999; -.
DR EnsemblFungi; SPBC27B12.10c.1; SPBC27B12.10c.1:pep; SPBC27B12.10c.
DR GeneID; 2540502; -.
DR KEGG; spo:SPBC27B12.10c; -.
DR PomBase; SPBC27B12.10c; tom7.
DR VEuPathDB; FungiDB:SPBC27B12.10c; -.
DR eggNOG; KOG4449; Eukaryota.
DR InParanoid; O42999; -.
DR PRO; PR:O42999; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005741; C:mitochondrial outer membrane; IBA:GO_Central.
DR GO; GO:0005742; C:mitochondrial outer membrane translocase complex; ISS:PomBase.
DR GO; GO:0005198; F:structural molecule activity; ISS:PomBase.
DR GO; GO:0030150; P:protein import into mitochondrial matrix; ISS:PomBase.
DR GO; GO:0045039; P:protein insertion into mitochondrial inner membrane; ISS:PomBase.
DR GO; GO:0045040; P:protein insertion into mitochondrial outer membrane; ISS:PomBase.
DR InterPro; IPR012621; Tom7.
DR Pfam; PF08038; Tom7; 1.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Mitochondrion outer membrane; Protein transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..52
FT /note="Mitochondrial import receptor subunit tom7"
FT /id="PRO_0000046766"
FT TOPO_DOM 1..19
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 20..36
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 37..52
FT /note="Mitochondrial intermembrane"
FT /evidence="ECO:0000250"
SQ SEQUENCE 52 AA; 6039 MW; B4F872374579F3B2 CRC64;
MQISEESKER LVKVFNIGKT VTHYGWIPLI LWLGYTQSNP KPQLMRVINP LA