TOM91_ARATH
ID TOM91_ARATH Reviewed; 94 AA.
AC O64497;
DT 07-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 25-MAY-2022, entry version 112.
DE RecName: Full=Mitochondrial import receptor subunit TOM9-1;
DE AltName: Full=Mitochondrial import receptor subunit TOM22 homolog 1;
DE AltName: Full=Translocase of outer membrane 22 kDa subunit homolog 1;
DE AltName: Full=Translocase of outer membrane 9 kDa subunit TOM9-1;
GN Name=TOM9-1; Synonyms=TOM22-1; OrderedLocusNames=At1g04070;
GN ORFNames=F20D22.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP TISSUE SPECIFICITY.
RX PubMed=14730085; DOI=10.1104/pp.103.033910;
RA Lister R., Chew O., Lee M.N., Heazlewood J.L., Clifton R., Parker K.L.,
RA Millar A.H., Whelan J.;
RT "A transcriptomic and proteomic characterization of the Arabidopsis
RT mitochondrial protein import apparatus and its response to mitochondrial
RT dysfunction.";
RL Plant Physiol. 134:777-789(2004).
CC -!- FUNCTION: Central component of the receptor complex responsible for the
CC recognition and translocation of cytosolically synthesized
CC mitochondrial preproteins. Together with TOM20 functions as the transit
CC peptide receptor at the surface of the mitochondrion outer membrane and
CC facilitates the movement of preproteins into the translocation pore (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Forms part of the preprotein translocase complex of the outer
CC mitochondrial membrane (TOM complex) which consists of at least 6
CC different proteins (TOM5, TOM6, TOM7, TOM20, TOM22/TOM9 and TOM40).
CC -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250};
CC Single-pass type II membrane protein {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, flowers, young cotyledons and
CC leaves. {ECO:0000269|PubMed:14730085}.
CC -!- SIMILARITY: Belongs to the Tom22 family. {ECO:0000305}.
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DR EMBL; AC002411; AAC16747.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE27651.1; -; Genomic_DNA.
DR EMBL; AY086260; AAM64333.1; -; mRNA.
DR EMBL; AK175541; BAD43304.1; -; mRNA.
DR PIR; T00965; T00965.
DR RefSeq; NP_563699.1; NM_100288.3.
DR AlphaFoldDB; O64497; -.
DR SMR; O64497; -.
DR STRING; 3702.AT1G04070.1; -.
DR SwissPalm; O64497; -.
DR PaxDb; O64497; -.
DR EnsemblPlants; AT1G04070.1; AT1G04070.1; AT1G04070.
DR GeneID; 839317; -.
DR Gramene; AT1G04070.1; AT1G04070.1; AT1G04070.
DR KEGG; ath:AT1G04070; -.
DR Araport; AT1G04070; -.
DR TAIR; locus:2020275; AT1G04070.
DR eggNOG; KOG4111; Eukaryota.
DR HOGENOM; CLU_172840_0_0_1; -.
DR InParanoid; O64497; -.
DR OMA; FEMQQAS; -.
DR OrthoDB; 1577431at2759; -.
DR PhylomeDB; O64497; -.
DR PRO; PR:O64497; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; O64497; baseline and differential.
DR Genevisible; O64497; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005742; C:mitochondrial outer membrane translocase complex; ISS:TAIR.
DR GO; GO:0015450; F:protein-transporting ATPase activity; ISS:TAIR.
DR GO; GO:0006626; P:protein targeting to mitochondrion; ISS:TAIR.
DR InterPro; IPR017411; Tom22_pln.
DR PANTHER; PTHR46867; PTHR46867; 1.
DR PIRSF; PIRSF038151; TOM9-2_plant; 1.
PE 2: Evidence at transcript level;
KW Membrane; Mitochondrion; Mitochondrion outer membrane; Protein transport;
KW Receptor; Reference proteome; Signal-anchor; Translocation; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..94
FT /note="Mitochondrial import receptor subunit TOM9-1"
FT /id="PRO_0000076109"
FT TOPO_DOM 1..48
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 49..66
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 67..94
FT /note="Mitochondrial intermembrane"
FT /evidence="ECO:0000255"
SQ SEQUENCE 94 AA; 9940 MW; 47996DDF5ADEFF3D CRC64;
MAPKKIGAGK GDSSILAKIS NYDIVSQGRR AACDAVYVSK KLLKSTGKAA WIAGTTFLIL
AVPLILELEQ DHRLGEIDFE QASLLGTPPV GAML
