TONB2_PSEAE
ID TONB2_PSEAE Reviewed; 270 AA.
AC Q9RMT3; Q7DCN0;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Protein tonB2;
GN Name=tonB2; OrderedLocusNames=PA0197;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=PAO6609;
RX PubMed=10689178; DOI=10.1111/j.1574-6968.2000.tb09002.x;
RA Zhao Q., Poole K.;
RT "A second tonB gene in Pseudomonas aeruginosa is linked to the exbB and
RT exbD genes.";
RL FEMS Microbiol. Lett. 184:127-132(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- FUNCTION: Interacts with outer membrane receptor proteins that carry
CC out high-affinity binding and energy dependent uptake into the
CC periplasmic space of specific substrates. It could act to transduce
CC energy from the cytoplasmic membrane to specific energy-requiring
CC processes in the outer membrane, resulting in the release into the
CC periplasm of ligands bound by these outer membrane proteins (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Homodimer. Forms a complex with the accessory proteins ExbB
CC and ExbD (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Single-pass
CC membrane protein {ECO:0000250}; Periplasmic side {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TonB family. {ECO:0000305}.
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DR EMBL; AF190125; AAF04082.1; -; Genomic_DNA.
DR EMBL; AE004091; AAG03586.1; -; Genomic_DNA.
DR PIR; H83619; H83619.
DR RefSeq; NP_248888.1; NC_002516.2.
DR RefSeq; WP_003117234.1; NZ_QZGA01000009.1.
DR AlphaFoldDB; Q9RMT3; -.
DR SMR; Q9RMT3; -.
DR STRING; 287.DR97_3154; -.
DR PaxDb; Q9RMT3; -.
DR EnsemblBacteria; AAG03586; AAG03586; PA0197.
DR GeneID; 879472; -.
DR KEGG; pae:PA0197; -.
DR PATRIC; fig|208964.12.peg.205; -.
DR PseudoCAP; PA0197; -.
DR HOGENOM; CLU_076057_2_0_6; -.
DR InParanoid; Q9RMT3; -.
DR OMA; DCYLHLK; -.
DR BioCyc; PAER208964:G1FZ6-199-MON; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.
DR GO; GO:0098797; C:plasma membrane protein complex; IBA:GO_Central.
DR GO; GO:0031992; F:energy transducer activity; IBA:GO_Central.
DR GO; GO:0015343; F:siderophore transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR003538; TonB.
DR InterPro; IPR006260; TonB/TolA_C.
DR InterPro; IPR037682; TonB_C.
DR Pfam; PF03544; TonB_C; 1.
DR PRINTS; PR01374; TONBPROTEIN.
DR TIGRFAMs; TIGR01352; tonB_Cterm; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..270
FT /note="Protein tonB2"
FT /id="PRO_0000287768"
FT TOPO_DOM 1..51
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 52..69
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 70..270
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT REGION 80..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..136
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..178
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 270 AA; 28821 MW; C02B19ABD85C52E3 CRC64;
MATPQPVDAR TQPWRETPGG DLVALGRPVR QALHLVRHNP AQGRVLSRRE TILLVLFALT
LHGAVIHWLS QQRTPALPEV PPQVPPMTIE FTAPAPPVVE PPPPEPLPPV VEEPPPPVVD
ENAVKPPPPK PVPKPKPKPK PQPRPKPAPK AVEPAPPAPP QPAAPPAPPA PAAAPAPLTP
PSANAGYLHN PAPEYPALAM RRGWEGTVLL RVHVLASGSP SEIQVQKSSG REALDQAAVK
AVKRWSFVPA KRGDKAEDGW VSVPIDFKLN
