ID   TONB_NEIGO              Reviewed;         283 AA.
AC   O06432;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Protein TonB;
GN   Name=tonB;
OS   Neisseria gonorrhoeae.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=485;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=FA19;
RX   PubMed=9140974; DOI=10.1046/j.1365-2958.1997.3421692.x;
RA   Biswas G.D., Anderson J.E., Sparling P.F.;
RT   "Cloning and functional characterization of Neisseria gonorrhoeae tonB,
RT   exbB and exbD genes.";
RL   Mol. Microbiol. 24:169-179(1997).
CC   -!- FUNCTION: Pathways of utilization of iron bound to transferrin,
CC       lactoferrin and hemoglobin but not to haemin or citrate where dependent
CC       on the TonB system.
CC   -!- SUBUNIT: The accessory proteins ExbB and ExbD seem to form a complex
CC       with TonB. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Single-pass
CC       membrane protein {ECO:0000250}; Periplasmic side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TonB family. {ECO:0000305}.
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DR   EMBL; U79563; AAC45286.1; -; Genomic_DNA.
DR   RefSeq; WP_003693736.1; NZ_WHPL01000002.1.
DR   AlphaFoldDB; O06432; -.
DR   SMR; O06432; -.
DR   PRIDE; O06432; -.
DR   GeneID; 66753585; -.
DR   OMA; SEAQAYN; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0031992; F:energy transducer activity; IEA:InterPro.
DR   GO; GO:0015343; F:siderophore transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR003538; TonB.
DR   InterPro; IPR006260; TonB/TolA_C.
DR   InterPro; IPR037682; TonB_C.
DR   Pfam; PF03544; TonB_C; 1.
DR   PRINTS; PR01374; TONBPROTEIN.
DR   TIGRFAMs; TIGR01352; tonB_Cterm; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW   Signal-anchor; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..283
FT                   /note="Protein TonB"
FT                   /id="PRO_0000196201"
FT   TOPO_DOM        1..5
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        6..27
FT                   /note="Helical; Signal-anchor"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        28..283
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          52..216
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..83
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        94..136
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   283 AA;  28749 MW;  3CD3F8353B445748 CRC64;
     MDKERILTPA VVFSVALLHL AIVALLWQAH KLPVIESGNV IEFVDLGDFG GGGGAPEGAG
     APAAPEPQPA PDPPKPVEPP KPVLKPAVTK KADADIQQPK EKPKPEEKPK PEPEPEAKPA
     PKPAEKPAEK PSEKPAEHSG NASAKAGSEQ GNGEGKGTGT KGDGTGRGEG SGKGSGGAKG
     EHGEGAGGSG GGTGVGSSKG NPLRANGSIP RPAYPALSME NDEQGMVVLS VLVSPGGHVE
     SVKVVKSSGF SRLDNAARKA AQNGHFQANA WTEFKVPVKF ELN