ID   TONB_YEREN              Reviewed;         255 AA.
AC   Q05740;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Protein TonB;
GN   Name=tonB;
OS   Yersinia enterocolitica.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=630;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8384290; DOI=10.1007/bf00282796;
RA   Koebnik R., Baeumler A.J., Heesemann J., Braun V., Hantke K.;
RT   "The TonB protein of Yersinia enterocolitica and its interactions with
RT   TonB-box proteins.";
RL   Mol. Gen. Genet. 237:152-160(1993).
CC   -!- FUNCTION: Interacts with outer membrane receptor proteins that carry
CC       out high-affinity binding and energy dependent uptake into the
CC       periplasmic space of specific substrates. It could act to transduce
CC       energy from the cytoplasmic membrane to specific energy-requiring
CC       processes in the outer membrane, resulting in the release into the
CC       periplasm of ligands bound by these outer membrane proteins (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. Forms a complex with the accessory proteins ExbB
CC       and ExbD (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Single-pass membrane
CC       protein; Periplasmic side.
CC   -!- SIMILARITY: Belongs to the TonB family. {ECO:0000305}.
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DR   EMBL; X67332; CAA47747.1; -; Genomic_DNA.
DR   PIR; S30290; S30290.
DR   RefSeq; WP_032905087.1; NZ_FKKS01000033.1.
DR   AlphaFoldDB; Q05740; -.
DR   SMR; Q05740; -.
DR   eggNOG; COG0810; Bacteria.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0031992; F:energy transducer activity; IEA:InterPro.
DR   GO; GO:0015343; F:siderophore transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR003538; TonB.
DR   InterPro; IPR006260; TonB/TolA_C.
DR   InterPro; IPR037682; TonB_C.
DR   Pfam; PF03544; TonB_C; 1.
DR   PRINTS; PR01374; TONBPROTEIN.
DR   TIGRFAMs; TIGR01352; tonB_Cterm; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport; Repeat;
KW   Signal-anchor; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..255
FT                   /note="Protein TonB"
FT                   /id="PRO_0000196213"
FT   TOPO_DOM        1..10
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        11..33
FT                   /note="Helical; Signal-anchor"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        34..255
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   REPEAT          72..73
FT                   /note="1-1"
FT   REPEAT          74..75
FT                   /note="1-2"
FT   REPEAT          76..77
FT                   /note="1-3"
FT   REPEAT          78..79
FT                   /note="1-4"
FT   REPEAT          80..81
FT                   /note="1-5"
FT   REPEAT          82..83
FT                   /note="1-6"
FT   REPEAT          94..95
FT                   /note="2-1"
FT   REPEAT          96..97
FT                   /note="2-2"
FT   REPEAT          98..99
FT                   /note="2-3"
FT   REPEAT          100..101
FT                   /note="2-4"
FT   REPEAT          102..103
FT                   /note="2-5"
FT   REPEAT          104..105
FT                   /note="2-6"
FT   REPEAT          107..108
FT                   /note="3-1"
FT   REPEAT          109..110
FT                   /note="3-2"
FT   REPEAT          111..112
FT                   /note="3-3"
FT   REGION          63..175
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          72..83
FT                   /note="6 X 2 AA tandem repeats of E-P"
FT   REGION          94..105
FT                   /note="6 X 2 AA tandem repeats of [LEIV]-P"
FT   REGION          107..112
FT                   /note="3 X 2 AA tandem repeats of K-P"
FT   COMPBIAS        73..89
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        90..107
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        108..142
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   255 AA;  27861 MW;  0EA7285FDEBD988E CRC64;
     MQLNKFFLGR WLTWPLAFSV GIHGSVIAAL LYVSVEQMRI QPEIEDAPIA VTMVNIDTFA
     APQPAAAEPQ AEPEPEPEPE PEPIDEAPPE PEVLPEPVPV PIPEPVKPKP KPVKKEVKKP
     EVKKPDVKKT VAPPDDKPFK SDEPALVSTN APVKSAPKAS VPGVSTSTGP KALSKAKPTY
     PARALALGVE GQVKVQYDID ENGRVTNVRI LEATPRNTFE REVKQVMRKW RFEAVAAKDY
     VTTVVFKIGG TTEMD